Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16769855 | 1.00 | MEN1 (0.34) | MEN1ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL8678507 | 0.74 | MEN1 (0.39) | MEN1ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL10591170 | 0.68 | CRBN (0.50) | MEN1ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL11911681 | 0.67 | PRKCA (0.33) | MEN1ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL7751354 | 0.67 | ALDH1A1 (0.36) | MEN1ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL28676565 | 0.67 | ALDH1A1 (0.36) | MEN1ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL6755435 | 0.66 | KMT2A (0.35) | MEN1ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL19264444 | 0.66 | KMT2A (0.35) | MEN1ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL14895194 | 0.65 | MEN1 (0.32) | MEN1ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL5868539 | 0.63 | CRBN (0.31) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216175-A | Polyoxoheterocyclic tetracylic derivatives | SRI INTERNATIONAL (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0479970-A1 | ANTIMALARIAL ANALOGS OF ARTEMISININ | SRI INTERNATIONAL (US) | 1992-04-15 | — | — | EP | disclosed |
| WO-1991014689-A1 | ANTIMALARIAL ANALOGS OF ARTEMISININ | SRI INTERNATIONAL (US) | 1991-10-03 | — | — | WO | disclosed |