SCHEMBL1677068

SCHEMBL1677068

CC(C)[C@H](C(N)=O)c1ccc(Cl)cc1

nearest known ligand 0.62

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR2 O15552 18/20 0.62
ADRB2 P07550 1/20 0.48
MEN1 O00255 1/20 0.47
LMNA P02545 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1677071 1.00 FFAR2 (0.62) FFAR2ADRB2MEN1LMNAKMT2A
SCHEMBL1677147 1.00 FFAR2 (0.62) FFAR2ADRB2MEN1LMNAKMT2A
SCHEMBL29639815 0.88 FFAR2 (0.47) FFAR2LMNA
SCHEMBL10614514 0.82 FFAR2 (0.61) FFAR2ADRB2MEN1LMNAKMT2A
SCHEMBL10614521 0.82 FFAR2 (0.61) FFAR2ADRB2MEN1LMNAKMT2A
SCHEMBL1405698 0.82 FFAR2 (0.65) FFAR2MEN1LMNAKMT2A
SCHEMBL1677207 0.82 FFAR2 (0.65) FFAR2MEN1LMNAKMT2A
SCHEMBL1780649 0.82 FFAR2 (0.65) FFAR2MEN1LMNAKMT2A
SCHEMBL3880453 0.82 FFAR2 (0.65) FFAR2MEN1LMNAKMT2A
SCHEMBL68169 0.82 FFAR2 (0.65) FFAR2MEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160243015-A1 SKIN LIGHTENING COMPOSITION CONOPCO, INC., D/B/A UNILEVER (US) 2016-08-25 US disclosed
US-8252564-B2 Burkholderia multivorans strain and methods of using same LG CHEM, LTD. (KR) 2012-08-28 US disclosed
US-20110097768-A1 Novel Burkholderia Multivorans LG 31-3, Amidase Produced From the Same, and Method for Resolution of Racemic Mixture Using the Same LG CHEM, LTD. (KR) 2011-04-28 US disclosed
WO-2007114668-A1 NOVEL BURKHOLDERIA MULTIVORANS LG 31-3, AMIDASE PRODUCED FROM THE SAME, AND METHOD FOR RESOLUTION OF RACEMIC MIXTURE USING THE SAME LG CHEM, LTD. (KR) 2007-10-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160243015-A1 SKIN LIGHTENING COMPOSITION TYR, MC1R, MITF FFAR2 4424/4885ADRB2 1224/4885MEN1 3777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.