Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 3/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | USP5 | P45974 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1677068 | 0.88 | FFAR2 (0.62) | FFAR2LMNA | |
| SCHEMBL1677147 | 0.88 | FFAR2 (0.62) | FFAR2LMNA | |
| SCHEMBL1677071 | 0.88 | FFAR2 (0.62) | FFAR2LMNA | |
| SCHEMBL11316797 | 0.83 | FFAR2 (0.42) | FFAR2HTTALDH1A1 | |
| SCHEMBL17892145 | 0.83 | ALOX5 (0.53) | FFAR2EPHX1SMN1; SMN2 | |
| SCHEMBL17892146 | 0.83 | ALOX5 (0.53) | FFAR2EPHX1SMN1; SMN2 | |
| SCHEMBL1483328 | 0.83 | CYP2D6 (0.54) | CYP2D6HIF1AKDM4EEPHX1LMNA | |
| SCHEMBL5475337 | 0.83 | CYP2D6 (0.54) | CYP2D6HIF1AKDM4EEPHX1LMNA | |
| SCHEMBL14749339 | 0.83 | CYP2D6 (0.54) | CYP2D6HIF1AKDM4EEPHX1LMNA | |
| SCHEMBL10160920 | 0.82 | TP53 (0.46) | FFAR2TYRALDH1A1SMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502543-A | Targeted protein compounds, pharmaceutical compositions and therapeutic applications thereof | 拜欧斯瑞克斯公司 | 2022-05-13 | — | — | CN | disclosed |