Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11872234 | 0.76 | KAT2B (0.37) | CASP3KAT2BMAPTALDH1A1KDM4E | |
| SCHEMBL12913013 | 0.70 | CNR2 (0.45) | MAPTATMKDM4E | |
| SCHEMBL8957218 | 0.70 | MAPT (0.68) | MAPTKMT2A | |
| SCHEMBL12913014 | 0.70 | CNR2 (0.70) | MAPTATMALDH1A1KDM4ENPC1 | |
| SCHEMBL3317990 | 0.70 | RECQL (0.55) | KAT2BMAPTGAANPC1MAPK1 | |
| SCHEMBL30512910 | 0.68 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL7808408 | 0.68 | CNR2 (0.45) | MAPTALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL12913017 | 0.68 | CNR2 (0.42) | MAPTATMALDH1A1KDM4ENPC1 | |
| SCHEMBL7818113 | 0.67 | CNR1 (0.56) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8916923 | 0.67 | NPC1 (0.54) | CASP3CA12CA1CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2132183-B1 | LISOFYLLINE ANALOGS AND METHODS FOR USE | Univ Virginia Patent Found (US) | 2015-06-03 | — | — | EP | disclosed |