Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16772015 | 0.76 | CASP3 (0.42) | KAT2BKMT2AMEN1RAB9AKDM4E | |
| SCHEMBL8957218 | 0.66 | MAPT (0.68) | KMT2AMAPTTSHR | |
| SCHEMBL3316327 | 0.64 | KAT2B (0.52) | KAT2BRAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL10485351 | 0.62 | PKM (0.55) | KAT2BKMT2AMEN1NPC1MAPK1 | |
| SCHEMBL3319604 | 0.62 | CNR2 (0.51) | KAT2BKMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL3312575 | 0.62 | CNR2 (0.51) | KAT2BKMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL765094 | 0.61 | KAT2B (0.46) | KAT2BKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL3317990 | 0.60 | RECQL (0.55) | KAT2BKMT2ARAB9ANPC1MAPK1 | |
| SCHEMBL11319689 | 0.59 | ADRB2 (0.42) | KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL11273816 | 0.59 | CA12 (0.34) | KAT2BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957776-A | HYPOTENSIVE AGENTS | DELMAR CHEMICALS LIMITED (CA) | 1976-05-18 | — | — | US | disclosed |