SCHEMBL16772133

SCHEMBL16772133

N#C/C(c1cc(C#N)cc(C#N)c1)=c1/cc(-c2ccc(C#N)cc2)/c(=C(\C#N)c2cc(C#N)cc(C#N)c2)cc1-c1ccc(C#N)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 1/20 0.40
SLC22A12 Q96S37 2/20 0.36
MAP4K4 O95819 1/20 0.36
CA2 P00918 3/20 0.35
CA12 O43570 1/20 0.35
CA3 P07451 1/20 0.35
CA6 P23280 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
GSK3B P49841 1/20 0.35
CA1 P00915 2/20 0.34
CYP11B2 P19099 2/20 0.34
XDH P47989 1/20 0.34
KIF11 P52732 2/20 0.33
MMP2 P08253 1/20 0.33
PTGS1 P23219 1/20 0.33
KDM1A O60341 1/20 0.33
MAOA P21397 1/20 0.33
CASP1 P29466 1/20 0.33
ENPP2 Q13822 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16772118 0.79 KIF11 (0.57) CYP11B2KIF11KDM1A
SCHEMBL16771997 0.77 RXRA (0.39) XDHKIF11
SCHEMBL16772035 0.77 MMP3 (0.47) MMP3SLC22A12MAP4K4CA2CA12
SCHEMBL16772032 0.76 KIF11 (0.41) MMP3SLC22A12MAP4K4CA2CA12
SCHEMBL18941841 0.73 MMP3 (0.34) MMP3CA2CA12CA3CA6
SCHEMBL16771982 0.73 KIF11 (0.45) GSK3BKIF11KDM1A
SCHEMBL18940992 0.73 MMP3 (0.34) MMP3CA2CA12CA3CA6
SCHEMBL18941810 0.73 MMP3 (0.34) MMP3CA2CA12CA3CA6
SCHEMBL24479418 0.69 MMP3 (0.37) MMP3CA2CA12CA3CA6
SCHEMBL18941813 0.68 MMP3 (0.33) MMP3KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150155490-A1 ORGANIC COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG DISPLAY CO., LTD. (KR) 2015-06-04 US disclosed