Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16773383 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HSD17B10HIF1ACYP1B1TDP1 | |
| SCHEMBL13428405 | 0.81 | ALDH1A1 (0.34) | ALDH1A1HSD17B10HIF1ACYP1B1P2RX4 | |
| SCHEMBL12928337 | 0.81 | POLB (0.42) | ALDH1A1HSD17B10HIF1AP2RX4TDP1 | |
| SCHEMBL20062872 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HSD17B10HIF1ACYP1B1TDP1 | |
| SCHEMBL13009193 | 0.80 | HSP90AA1 (0.47) | ALDH1A1HSD17B10HIF1AP2RX4TDP1 | |
| SCHEMBL13615793 | 0.79 | LMNA (0.33) | P2RX4TSHRLMNAMAPK1SCN4A | |
| SCHEMBL13615975 | 0.79 | LMNA (0.33) | P2RX4TSHRLMNAMAPK1SCN4A | |
| SCHEMBL13456449 | 0.79 | HSP90AA1 (0.33) | ALDH1A1HSD17B10HIF1ACYP1B1P2RX4 | |
| SCHEMBL13009207 | 0.77 | HSP90AA1 (0.40) | ALDH1A1HSD17B10CYP1B1P2RX4TSHR | |
| SCHEMBL13009244 | 0.77 | HSP90AA1 (0.40) | ALDH1A1HSD17B10CYP1B1P2RX4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10446759-B2 | Phenanthrene compounds for organic electronic devices | MERCK PATENT GMBH (DE) | 2019-10-15 | — | — | US | disclosed |
| EP-2858980-B1 | PHENANTHRENES FOR USE IN ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-06-26 | — | — | EP | disclosed |
| US-20180102479-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-04-12 | — | — | US | disclosed |
| US-20180102479-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-04-12 | — | — | US | disclosed |
| US-9799833-B2 | Phenanthrene compounds for organic electronic devices | MERCK PATENT GMBH (DE) | 2017-10-24 | — | — | US | disclosed |
| US-9799833-B2 | Phenanthrene compounds for organic electronic devices | MERCK PATENT GMBH (DE) | 2017-10-24 | — | — | US | disclosed |
| US-20150155491-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-06-04 | — | — | US | disclosed |
| US-20150155491-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10446759-B2 | Phenanthrene compounds for organic electronic devices | PAH, CYP1A1, AHR | ALDH1A1 1334/4885HSD17B10 1425/4885HIF1A 3726/4885 |
| US-20150155491-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | PAH, CYP1A1, AHR | ALDH1A1 1334/4885HSD17B10 1425/4885HIF1A 3726/4885 |
| US-20180102479-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | PAH, CYP1A1, AHR | ALDH1A1 1334/4885HSD17B10 1425/4885HIF1A 3726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.