SCHEMBL13615975

SCHEMBL13615975

C1=Cc2ccccc2N(c2ccc3c4ccccc4c4c5ccccc5c5ccccc5c4c3c2)c2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
SCN4A P35499 1/20 0.33
SCN5A Q14524 1/20 0.33
SCN9A Q15858 1/20 0.33
P2RX4 Q99571 7/20 0.33
P2RX1 P51575 1/20 0.30
P2RX3 P56373 1/20 0.30
P2RX7 Q99572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13615793 1.00 LMNA (0.33) LMNATSHRMAPK1SCN4ASCN5A
SCHEMBL27339994 0.83 LMNA (0.37) LMNATSHRMAPK1SCN4ASCN5A
SCHEMBL13651484 0.80
SCHEMBL13428410 0.79 P2RX4 (0.34) LMNATSHRMAPK1SCN4ASCN5A
SCHEMBL16773282 0.79 ALDH1A1 (0.45) LMNATSHRMAPK1SCN4ASCN5A
SCHEMBL13615825 0.79 TERT (0.35)
SCHEMBL17552437 0.79 LMNA (0.31) LMNATSHRMAPK1SCN4ASCN5A
SCHEMBL13508005 0.79 PTPN1 (0.32)
SCHEMBL13508085 0.79 PTGER4 (0.36)
SCHEMBL13339235 0.78 MGLL (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090273278-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-11-05 US disclosed
US-20090273278-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090273278-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OCIAD1, OCIAD2, ORMDL3 LMNA 3600/4885TSHR 4759/4885MAPK1 807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.