SCHEMBL16773295

SCHEMBL16773295

c1ccc(-c2ccc(Nc3ccc4ccc5ccccc5c4c3)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.55
HSD17B10 Q99714 6/20 0.55
CYP3A4 P08684 2/20 0.55
HPGD P15428 2/20 0.55
HIF1A Q16665 1/20 0.48
CYP1B1 Q16678 1/20 0.48
TSHR P16473 3/20 0.44
TDP1 Q9NUW8 2/20 0.44
CYP2A6 P11509 1/20 0.44
ALOX15 P16050 2/20 0.44
TP53 P04637 1/20 0.44
CDC25B P30305 1/20 0.44
ATM Q13315 1/20 0.44
MAPT P10636 4/20 0.43
MEN1 O00255 1/20 0.43
AR P10275 1/20 0.43
KMT2A Q03164 1/20 0.43
ALOX12 P18054 1/20 0.43
PTGS1 P23219 1/20 0.43
SLC6A2 P23975 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16541617 0.96 ALDH1A1 (0.52) ALDH1A1HSD17B10CYP3A4HPGDHIF1A
SCHEMBL24056412 0.93 ALDH1A1 (0.50) ALDH1A1HSD17B10CYP3A4HPGDHIF1A
SCHEMBL25734746 0.93 ALDH1A1 (0.50) ALDH1A1HSD17B10CYP3A4HPGDHIF1A
SCHEMBL17701124 0.91 ALDH1A1 (0.58) ALDH1A1HSD17B10CYP3A4HPGDHIF1A
SCHEMBL16755478 0.90 ALDH1A1 (0.67) ALDH1A1HSD17B10CYP3A4HPGDHIF1A
SCHEMBL31377546 0.90 ALDH1A1 (0.67) ALDH1A1HSD17B10CYP3A4HPGDHIF1A
SCHEMBL25734716 0.89 ALDH1A1 (0.50) ALDH1A1HSD17B10CYP3A4HPGDHIF1A
SCHEMBL25734581 0.89 ALDH1A1 (0.56) ALDH1A1HSD17B10CYP3A4HPGDHIF1A
SCHEMBL24056320 0.89 ALDH1A1 (0.56) ALDH1A1HSD17B10CYP3A4HPGDHIF1A
SCHEMBL24948768 0.89 HPRT1 (0.48) ALDH1A1HSD17B10CYP3A4HPGDHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4258372-A1 ORGANIC LIGHT-EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-10-11 EP disclosed
US-20230157159-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2023-05-18 US disclosed
US-20230157159-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2023-05-18 US disclosed
WO-2023287228-A1 ORGANIC LIGHT EMITTING DEVICE 주식회사 엘지화학 2023-01-19 WO disclosed
WO-2022131869-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2022-06-23 WO disclosed
WO-2021235906-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME 주식회사 엘지화학 2021-11-25 WO disclosed
US-10446759-B2 Phenanthrene compounds for organic electronic devices MERCK PATENT GMBH (DE) 2019-10-15 US disclosed
EP-2858980-B1 PHENANTHRENES FOR USE IN ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-06-26 EP disclosed
US-9960357-B2 Spiro-type compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2018-05-01 US disclosed
US-20180102479-A1 PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2018-04-12 US disclosed
US-20180102479-A1 PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2018-04-12 US disclosed
US-20170365787-A1 SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2017-12-21 US disclosed
US-9799833-B2 Phenanthrene compounds for organic electronic devices MERCK PATENT GMBH (DE) 2017-10-24 US disclosed
US-9799833-B2 Phenanthrene compounds for organic electronic devices MERCK PATENT GMBH (DE) 2017-10-24 US disclosed
US-20150155491-A1 PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-06-04 US disclosed
US-20150155491-A1 PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-06-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10446759-B2 Phenanthrene compounds for organic electronic devices PAH, CYP1A1, AHR ALDH1A1 1334/4885HSD17B10 1425/4885CYP3A4 22/4885
US-20150155491-A1 PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES PAH, CYP1A1, AHR ALDH1A1 1334/4885HSD17B10 1425/4885CYP3A4 22/4885
US-20230157159-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME NR0B1, AHR, ARL1 ALDH1A1 628/4885HSD17B10 1117/4885CYP3A4 929/4885
US-20170365787-A1 SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, NR2E3, LEF1 ALDH1A1 8/4885HSD17B10 1042/4885CYP3A4 236/4885
US-20180102479-A1 PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES PAH, CYP1A1, AHR ALDH1A1 1334/4885HSD17B10 1425/4885CYP3A4 22/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.