Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 2/20 | 0.44 |
| ▸ | GABRD | O14764 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12070210 | 0.90 | KDM4E (0.54) | KDM4EMAPTHPGDHSD17B10GLA | |
| SCHEMBL2472033 | 0.89 | CYP2A6 (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL24362903 | 0.87 | KDM4E (0.41) | KDM4EMAPTHPGDHSD17B10GLA | |
| SCHEMBL24363258 | 0.87 | KDM4E (0.42) | KDM4EMAPTHPGDHSD17B10GLA | |
| SCHEMBL4567323 | 0.86 | HPRT1 (0.52) | KDM4EMAPTHPGDHSD17B10GLA | |
| SCHEMBL18086160 | 0.86 | ALDH1A1 (0.52) | KDM4EMAPTHPGDHSD17B10GLA | |
| SCHEMBL2802294 | 0.86 | MAPT (0.52) | KDM4EMAPTHPGDGABRPGABRD | |
| SCHEMBL24363213 | 0.85 | GABRP (0.47) | KDM4EMAPTHPGDGABRPGABRD | |
| SCHEMBL24363026 | 0.84 | GABRP (0.42) | KDM4EMAPTHPGDHSD17B10GABRP | |
| SCHEMBL31135087 | 0.84 | GABRP (0.42) | KDM4EMAPTHPGDHSD17B10GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10446759-B2 | Phenanthrene compounds for organic electronic devices | MERCK PATENT GMBH (DE) | 2019-10-15 | — | — | US | disclosed |
| EP-2858980-B1 | PHENANTHRENES FOR USE IN ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-06-26 | — | — | EP | disclosed |
| US-20180102479-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-04-12 | — | — | US | disclosed |
| US-20180102479-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-04-12 | — | — | US | disclosed |
| US-9799833-B2 | Phenanthrene compounds for organic electronic devices | MERCK PATENT GMBH (DE) | 2017-10-24 | — | — | US | disclosed |
| US-9799833-B2 | Phenanthrene compounds for organic electronic devices | MERCK PATENT GMBH (DE) | 2017-10-24 | — | — | US | disclosed |
| US-20150155491-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-06-04 | — | — | US | disclosed |
| US-20150155491-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10446759-B2 | Phenanthrene compounds for organic electronic devices | PAH, CYP1A1, AHR | KDM4E 1217/4885MAPT 1204/4885HPGD 309/4885 |
| US-20150155491-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | PAH, CYP1A1, AHR | KDM4E 1217/4885MAPT 1204/4885HPGD 309/4885 |
| US-20180102479-A1 | PHENANTHRENE COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES | PAH, CYP1A1, AHR | KDM4E 1217/4885MAPT 1204/4885HPGD 309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.