Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.63 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.59 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19774465 | 0.91 | MTNR1A (0.62) | ALOX5OR51E2TAAR1TSHRMAPK1 | |
| SCHEMBL29604390 | 0.82 | PTPN1 (0.82) | ALOX5OR51E2TAAR1TSHRMAPK1 | |
| SCHEMBL17780116 | 0.82 | PTPN1 (0.82) | ALOX5OR51E2TAAR1TSHRMAPK1 | |
| Zingerone SCHEMBL29828498 | 0.82 | ALOX5 (0.74) | ALOX5OR51E2TAAR1TSHRMAPK1 | |
| Zingerone SCHEMBL14763994 | 0.82 | ALOX5 (0.74) | ALOX5OR51E2TAAR1TSHRMAPK1 | |
| Zingerone SCHEMBL119051 | 0.82 | ALOX5 (0.74) | ALOX5OR51E2TAAR1TSHRMAPK1 | |
| SCHEMBL26249522 | 0.82 | ALOX5 (0.65) | ALOX5OR51E2TAAR1TSHRMAPK1 | |
| SCHEMBL10907682 | 0.82 | ALOX5 (0.65) | ALOX5OR51E2TAAR1TSHRMAPK1 | |
| Zingerone SCHEMBL29378477 | 0.82 | ALOX5 (0.74) | ALOX5OR51E2TAAR1TSHRMAPK1 | |
| SCHEMBL29740697 | 0.81 | PTPN1 (0.79) | ALOX5OR51E2TAAR1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2416795-B1 | INHIBITORS OF COGNITIVE DECLINE | COGNITION THERAPEUTICS INC (US) | 2015-06-03 | — | — | EP | disclosed |