Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS3 | P17931 | 4/20 | 0.42 |
| ▸ | LGALS4 | P56470 | 3/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.33 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28423018 | 0.86 | LGALS3 (0.42) | LGALS3LGALS4NPC1PTPN1MAPT | |
| SCHEMBL28430166 | 0.84 | LGALS3 (0.47) | LGALS3LGALS4CYP2C19PTPN1MAPT | |
| SCHEMBL20557379 | 0.83 | HTT (0.38) | LGALS3LGALS4NPC1CYP2C19PTPN1 | |
| SCHEMBL16774476 | 0.81 | ADRB2 (0.45) | LGALS3LGALS4NPC1PTPN1MAPT | |
| SCHEMBL28427525 | 0.81 | NPC1 (0.40) | LGALS3LGALS4L3MBTL1NPC1LMNA | |
| SCHEMBL28562523 | 0.81 | NPC1 (0.40) | LGALS3LGALS4L3MBTL1NPC1LMNA | |
| SCHEMBL28422851 | 0.80 | KMT2A (0.38) | LGALS3LGALS4L3MBTL1NPC1LMNA | |
| SCHEMBL16774479 | 0.78 | LGALS3 (0.37) | LGALS3LGALS4FLT1FLT4KDR | |
| SCHEMBL16774750 | 0.76 | ABL1 (0.40) | LGALS3LGALS4FLT1FLT4KDR | |
| SCHEMBL18298145 | 0.75 | FLT1 (0.36) | LGALS3LGALS4FLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184112-B1 | SYNTHETIC INTERMEDIATE OF 1-(2-DEOXY-2-FLUORO-4-THIO-ß-D-ARABINOFURANOSYL)CYTOSINE | FUJIFILM CORP (JP) | 2020-12-23 | — | — | EP | disclosed |
| CN-107011168-B | Synthesis intermediates of cytosines and synthesis intermediates of thionucleosides | 富士胶片株式会社 | 2020-06-09 | — | — | CN | disclosed |
| EP-3184112-A1 | SYNTHETIC INTERMEDIATE OF 1-(2-DEOXY-2-FLUORO-4-THIO-SS-D-ARABINOFURANOSYL)CYTOSINE | Fujifilm Corporation (JP) | 2017-06-28 | — | — | EP | disclosed |
| EP-2883866-A1 | INTERMEDIATE FOR SYNTHESIS OF 1-(2-DEOXY-2-FLUORO-4-THIO-beta-D-ARABINOFURANOSYL) CYTOSINE, INTERMEDIATE FOR SYNTHESIS OF THIONUCLEOSIDE, AND METHODS FOR PRODUCING THESE INTERMEDIATES | FUJIFILM Corporation (JP) | 2015-06-17 | — | — | EP | disclosed |