Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | LGALS3 | P17931 | 4/20 | 0.43 |
| ▸ | LGALS4 | P56470 | 4/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28425890 | 0.89 | LGALS3 (0.46) | ADRB2ADRB1ADRB3NT5ELGALS3 | |
| SCHEMBL28423018 | 0.83 | LGALS3 (0.42) | LGALS3LGALS4PTPN1MAPTNPC1 | |
| SCHEMBL16774751 | 0.81 | LGALS3 (0.42) | LGALS3LGALS4PTPN1MAPTALDH1A1 | |
| SCHEMBL28430166 | 0.81 | LGALS3 (0.47) | LGALS3LGALS4PTPN1MAPTALDH1A1 | |
| SCHEMBL20557379 | 0.80 | HTT (0.38) | LGALS3LGALS4PTPN1ALDH1A1NPC1 | |
| SCHEMBL16774475 | 0.78 | POLB (0.41) | NT5ELGALS3LGALS4PTPN2PTPN1 | |
| SCHEMBL28427525 | 0.77 | NPC1 (0.40) | ADRB2ADRB1ADRB3NT5ELGALS3 | |
| SCHEMBL28562523 | 0.77 | NPC1 (0.40) | ADRB2ADRB1ADRB3NT5ELGALS3 | |
| SCHEMBL17471056 | 0.73 | ALDH1A1 (0.51) | ADRB2ADRB1ADRB3NT5EPTPN2 | |
| SCHEMBL15481817 | 0.73 | ALDH1A1 (0.51) | ADRB2ADRB1ADRB3NT5EPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184112-B1 | SYNTHETIC INTERMEDIATE OF 1-(2-DEOXY-2-FLUORO-4-THIO-ß-D-ARABINOFURANOSYL)CYTOSINE | FUJIFILM CORP (JP) | 2020-12-23 | — | — | EP | disclosed |
| CN-107011168-B | Synthesis intermediates of cytosines and synthesis intermediates of thionucleosides | 富士胶片株式会社 | 2020-06-09 | — | — | CN | disclosed |
| EP-3184112-A1 | SYNTHETIC INTERMEDIATE OF 1-(2-DEOXY-2-FLUORO-4-THIO-SS-D-ARABINOFURANOSYL)CYTOSINE | Fujifilm Corporation (JP) | 2017-06-28 | — | — | EP | disclosed |
| EP-2883866-A1 | INTERMEDIATE FOR SYNTHESIS OF 1-(2-DEOXY-2-FLUORO-4-THIO-beta-D-ARABINOFURANOSYL) CYTOSINE, INTERMEDIATE FOR SYNTHESIS OF THIONUCLEOSIDE, AND METHODS FOR PRODUCING THESE INTERMEDIATES | FUJIFILM Corporation (JP) | 2015-06-17 | — | — | EP | disclosed |