SCHEMBL16775264

SCHEMBL16775264

CCCC(=O)NC(=O)C=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 3/20 0.48
HDAC1 Q13547 3/20 0.48
HDAC2 Q92769 3/20 0.48
HDAC8 Q9BY41 3/20 0.48
HDAC6 Q9UBN7 1/20 0.48
CTSD P07339 1/20 0.46
MAPT P10636 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
CASP2 P42575 1/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
TRPA1 O75762 1/20 0.38
TP53 P04637 1/20 0.36
FFAR3 O14843 2/20 0.36
NPC1 O15118 1/20 0.35
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2933109 0.79 HDAC3 (0.46) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL27398881 0.79 HDAC3 (0.46) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL1643947 0.79 HDAC3 (0.63) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL18270932 0.78 ALDH1A1 (0.46) HDAC1HDAC2CASP2TRPA1TSHR
SCHEMBL16748699 0.77 CASP2 (0.46) HDAC1HDAC2CASP2TRPA1TSHR
SCHEMBL10036960 0.77 ICMT (0.43) MAPTMEN1KMT2ANPSR1TRPA1
Water SCHEMBL29155573 0.76 HDAC3 (0.60) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL10002235 0.76 MEN1 (0.38) MAPTMEN1KMT2ANPSR1CASP2
SCHEMBL4318511 0.76 HRH3 (0.56) MAPTMEN1KMT2ANPSR1TP53
SCHEMBL18265398 0.74 SLC22A1 (0.42) MEN1KMT2ATRPA1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015080803-A1 ANTI-AGGLOMERANTS FOR CONTROLLING GAS HYDRATES ECOLAB USA INC. (US) 2015-06-04 WO disclosed