SCHEMBL16775347

SCHEMBL16775347

CC1=CC(=Nc2cc(C)c(O)c(C)c2)C=C(C)C1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2B6 P20813 1/20 0.39
CTH P32929 1/20 0.38
BRD4 O60885 2/20 0.37
MAPT P10636 5/20 0.37
KDM4E B2RXH2 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
USP2 O75604 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
TXNRD1 Q16881 1/20 0.36
TXNRD3 Q86VQ6 1/20 0.36
TXNRD2 Q9NNW7 1/20 0.36
PTGS1 P23219 4/20 0.35
PTGS2 P35354 4/20 0.35
ALOX5 P09917 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13525184 0.84 KMT2A (0.41) CYP2C9CYP1A2CYP3A4CYP2D6CTH
SCHEMBL13525206 0.82 TXNRD1 (0.57) CYP2C9CYP1A2CYP3A4MAPTMEN1
SCHEMBL13525207 0.81 ALDH1A1 (0.37) CYP1A2CYP3A4MAPTKDM4EMEN1
SCHEMBL1783165 0.79 MAPT (0.38) MAPTKDM4EMEN1KMT2AUSP2
SCHEMBL13525197 0.77 CYP3A4 (0.41) CYP3A4MAPTKDM4EMEN1KMT2A
SCHEMBL11787390 0.74 CA1 (0.37) CYP2C9CYP1A2CYP3A4CYP2D6CYP2B6
SCHEMBL13525236 0.72 MAPT (0.38) CYP2C9CYP3A4MAPTKDM4EMEN1
SCHEMBL13010086 0.72 AGTR1 (0.39) CYP2D6MAPTKDM4EMEN1KMT2A
SCHEMBL13525196 0.69 CA12 (0.41) CYP3A4MAPTMEN1KMT2ACA1
SCHEMBL16309127 0.68 KMT2A (0.40) BRD4MAPTKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9052292-B2 Method of determining a concentration of nitrate HACH LANGE GMBH (DE) 2015-06-09 US disclosed
US-9052292-B2 Method of determining a concentration of nitrate HACH LANGE GMBH (DE) 2015-06-09 US disclosed