Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.34 |
| ▸ | VCP | P55072 | 2/20 | 0.33 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16776124 | 0.84 | CNR2 (0.38) | SIRT2KMOVCPRPS6KA2 | |
| SCHEMBL16776190 | 0.83 | FAAH (0.37) | FAAHADORA2A | |
| SCHEMBL16776263 | 0.83 | FAAH (0.39) | FAAH | |
| SCHEMBL16775849 | 0.82 | KDM4C (0.34) | ADORA2AKMOVCPRPS6KA2CA9 | |
| SCHEMBL16776200 | 0.82 | FAAH (0.39) | FAAH | |
| SCHEMBL16775907 | 0.80 | PHGDH (0.39) | KMOVCP | |
| SCHEMBL16776477 | 0.79 | PTGS1 (0.40) | FAAH | |
| SCHEMBL16776050 | 0.79 | PRMT5 (0.38) | FAAHRPS6KA2 | |
| SCHEMBL16775858 | 0.79 | RPS6KA2 (0.36) | ADORA2AKMORPS6KA2CA9 | |
| SCHEMBL16775859 | 0.79 | RPS6KA2 (0.33) | ADORA2AKMOVCPRPS6KA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150152108-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE LLC | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152108-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | SIRT1, SIRT3, SIRT2 | FAAH 977/4885SIRT2 3/4885ADORA2A 2325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.