SCHEMBL1677897

SCHEMBL1677897

CCN(O)c1cc([N+](=O)[O-])c(N)cc1Cl

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.46
CYP3A4 P08684 2/20 0.46
MAPT P10636 8/20 0.40
VCAM1 P19320 3/20 0.40
LMNA P02545 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
TSHR P16473 2/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
HCAR3 P49019 1/20 0.37
TDP1 Q9NUW8 3/20 0.37
POLB P06746 1/20 0.37
ALOX15 P16050 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1678316 0.84 TSHR (0.42) ALDH1A1CYP3A4MAPTLMNAMEN1
SCHEMBL14896151 0.83 ALDH1A1 (0.44) ALDH1A1MAPTVCAM1MEN1KMT2A
SCHEMBL19513951 0.77 ALDH1A1 (0.48) ALDH1A1CYP3A4MAPTVCAM1LMNA
SCHEMBL7473931 0.74 ALDH1A1 (0.54) ALDH1A1CYP3A4MAPTLMNAMEN1
SCHEMBL1193334 0.73 ALDH1A1 (0.60) ALDH1A1CYP3A4MAPTLMNAMEN1
SCHEMBL30458055 0.73 ALDH1A1 (0.60) ALDH1A1CYP3A4MAPTLMNAMEN1
SCHEMBL838256 0.73 ALDH1A1 (0.71) ALDH1A1CYP3A4MAPTVCAM1LMNA
SCHEMBL1886680 0.73 ALDH1A1 (0.51) ALDH1A1CYP3A4MAPTLMNAMEN1
SCHEMBL1913458 0.73 TSHR (0.51) ALDH1A1CYP3A4MAPTLMNAMEN1
SCHEMBL9651865 0.73 MAPT (0.55) ALDH1A1CYP3A4MAPTLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4362906-A1 COMPOSITION COMPRISING SHEA, AN ALKYL(POLY)GLYCOSIDE, A POLYSACCHARIDE AND A DYE L'OREAL (FR) 2024-05-08 EP disclosed
WO-2023275170-A1 COMPOSITION COMPRISING AT LEAST ONE ALKANOLAMINE, A (META)SILICATE, GLYCINE AND 1,3-PROPANEDIOL L'OREAL (FR) 2023-01-05 WO disclosed
WO-2023275187-A1 COMPOSITION COMPRISING SHEA, AN ALKYL(POLY)GLYCOSIDE, A POLYSACCHARIDE AND A DYE L'OREAL (FR) 2023-01-05 WO disclosed
EP-3544576-A1 DYE COMPOSITION COMPRISING 12-HYDROXYSTEARIC ACID, AN ORGANIC AMINE AND A DYE L'Oréal (FR) 2019-10-02 EP disclosed
WO-2018096132-A1 DYE COMPOSITION COMPRISING 12-HYDROXYSTEARIC ACID, AN ORGANIC AMINE AND A DYE L'OREAL (FR) 2018-05-31 WO disclosed
CN-107501991-A Three aromatic azo methine direct dyess, colouring compositions, method and purposes comprising at least one unit from resorcinol 欧莱雅 2017-12-22 CN disclosed
CN-107252397-A Include fatty material and organic phospho acid composition, the method and apparatus using it 莱雅公司 2017-10-17 CN disclosed
CN-107049807-A For dyeing keratinous fibres and/or the double reagent of bleaching 欧莱雅 2017-08-18 CN disclosed
CN-103998531-B Three aromatic azo methine direct dyess, dye composite, implementation and the purposes for including at least one such dyestuff 欧莱雅 2017-07-28 CN disclosed
US-9578944-B2 Compositions and methods for altering the appearance of hair L'OREAL (FR) 2017-02-28 US disclosed
WO-2011076647-A2 INVERSE EMULSION FOR TREATING THE HAIR COMPRISING A PARTICULAR FATTY SUBSTANCE AND AN ALKALINE AGENT L'OREAL (FR) 2011-06-30 WO disclosed
WO-2011076665-A1 AGENT IN TWO OR MORE PARTS, IN EMULSION FORM, FOR DYEING AND/OR BLEACHING KERATIN FIBRES L'OREAL (FR) 2011-06-30 WO disclosed
WO-2011045526-A2 COMPOSITION INCLUDING A GLYCERIDE AND AN ORGANOPHOSPHONIC ACID OR ONE OF THE SALTS THEREOF, DYEING OR COLOUR-LIGHTENING METHOD IMPLEMENTING SAME AND DEVICES L'OREAL (FR) 2011-04-21 WO disclosed
CN-1277528-C Dyeing compson. for kerationous fibres comprising particular dicationic diazo dye OREAL (FR) 2006-10-04 CN disclosed
CN-1796371-A Dicationic bis-hydrazone compound, dye composition comprising at least one such compound, implementation process therefor and uses thereof OREAL (FR) 2006-07-05 CN disclosed
CN-1245150-C Composition containing specific single cation monoazo dye for dyeing human cutin fiber OREAL (FR) 2006-03-15 CN disclosed
CN-1201719-C Specific amino silicone containing dye composition for body's cutin fiber OREAL (FR) 2005-05-18 CN disclosed
US-20040205903-A1 Dyeing composition comprising a cationic pyrrolidine-based para-phenylenefiamine, a tertiary para-phenylenediamine and a benzomorpholine coupler, methods and uses L'OREAL (FR) 2004-10-21 US disclosed
CN-1416798-A Specific amino silicone containing dye composition for body's cutin fiber OREAL (FR) 2003-05-14 CN disclosed
CN-1410047-A Composition containing specific single cation monoazo dye for dyeing human cutin fiber OREAL (FR) 2003-04-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040205903-A1 Dyeing composition comprising a cationic pyrrolidine-based para-phenylenefiamine, a tertiary para-phenylenediamine and a benzomorpholine coupler, methods and uses CDC73, KRT18, PAH ALDH1A1 1045/4885CYP3A4 246/4885MAPT 1091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.