Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.48 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11548194 | 0.93 | ALDH1A1 (0.63) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL29596496 | 0.91 | ALDH1A1 (0.71) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL1193334 | 0.91 | ALDH1A1 (0.60) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL30458055 | 0.91 | ALDH1A1 (0.60) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL1192850 | 0.91 | ALDH1A1 (0.71) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL1725673 | 0.89 | ALDH1A1 (0.69) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL4090172 | 0.89 | ALDH1A1 (0.58) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL30606309 | 0.89 | ALDH1A1 (0.58) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL9069658 | 0.87 | ALDH1A1 (0.56) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL359519 | 0.85 | TSHR (0.60) | ALDH1A1CYP3A4TDP1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104876887-A | Benzofuroxan derivative and preparation method and application thereof | UNIV YANTAI | 2015-09-02 | — | — | CN | claimed |
| CN-109081813-B | Benzoheterocycles compounds and application thereof in treating cancers | 海创药业股份有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-109081813-A | The purposes of a kind of benzo-heterocycle compound and its treating cancer | 成都海创药业有限公司 | 2018-12-25 | — | — | CN | disclosed |
| US-8664348-B2 | 2,4,5-triaminophenols and related compounds | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-03-04 | — | — | US | disclosed |
| US-8580910-B2 | 2,4,5-triaminophenols and related compounds | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-11-12 | — | — | US | disclosed |
| US-20130204041-A1 | 2,4,5-TRIAMINOPHENOLS AND RELATED COMPOUNDS | E I DU PONT DE NEMOURS AND COMPAN (US) | 2013-08-08 | — | — | US | disclosed |
| US-20130172621-A1 | INTEGRATED PROCESSES FOR THE PREPARATION OF POLYBENZIMIDAZOLE PRECURSORS | E.I.DU PONT DE NEMOURS AND COMPANY (US) | 2013-07-04 | — | — | US | disclosed |
| US-20130158296-A1 | PROCESS FOR THE SYNTHESIS OF 1-AMINO-3-HALO-4,6-DINITROBENZENE | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-20 | — | — | US | disclosed |
| US-20130158296-A1 | PROCESS FOR THE SYNTHESIS OF 1-AMINO-3-HALO-4,6-DINITROBENZENE | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-20 | — | — | US | disclosed |
| US-20130053573-A1 | 2,4,5-TRIAMINOPHENOLS AND RELATED COMPOUNDS | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-02-28 | — | — | US | disclosed |
| WO-2004033415-A1 | NITROANILINE-BASED ALKYLATING AGENTS AND THEIR USE AS PRODRUGS | AUCKLAND UNISERVICES LIMITED (NZ) | 2004-04-22 | — | — | WO | disclosed |
| EP-0280156-B1 | PROCESS FOR THE PREPARATION OF ACETOACETYLARYLAMIDES-HETEROARYLAMIDES RESPECTIVELY OF DEACTIVED AROMATIC COMPOUNDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-11 | — | — | EP | disclosed |
| EP-0280156-A2 | Process for the preparation of acetoacetylarylamides-heteroarylamides respectively of deactived aromatic compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-31 | — | — | EP | disclosed |
| US-4619993-A | Azo compounds having a 2,4-dinitro-5-thiocyanophenyl diazo component radical | SANDOZ LTD. (CH) | 1986-10-28 | — | — | US | disclosed |
| US-4264326-A | COLORFASTNESS | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1981-04-28 | — | — | US | disclosed |
| US-4137228-A | HIGH TINCTORIAL STRENGTH, COLORFASTNESS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-01-30 | — | — | US | disclosed |
| US-4033945-A | Water-soluble trisazo 8-amino-naphthol-1 dyes | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1977-07-05 | — | — | US | disclosed |
| US-3984405-A | PYRIDO(3,2-B)(1,4)OXAZIN-3(4H)-ONES | E. R. SQUIBB & SONS, INC. (US) | 1976-10-05 | — | — | US | disclosed |
| US-3941832-A | Oxime ethers and pesticidal preparations containing them | CIBA-GEIGY AG (CH) | 1976-03-02 | — | — | US | disclosed |
| US-3941839-A | HERBICIDE | CIBA-GEIGY AG (CH) | 1976-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172621-A1 | INTEGRATED PROCESSES FOR THE PREPARATION OF POLYBENZIMIDAZOLE PRECURSORS | PAH, PUF60, PARG | ALDH1A1 1579/4885CYP3A4 7/4885MAPT 712/4885 |
| US-20130053573-A1 | 2,4,5-TRIAMINOPHENOLS AND RELATED COMPOUNDS | WDR48, DDX41, DDX42 | ALDH1A1 1719/4885CYP3A4 188/4885MAPT 358/4885 |
| US-20130158296-A1 | PROCESS FOR THE SYNTHESIS OF 1-AMINO-3-HALO-4,6-DINITROBENZENE | DDC, AADAT, AASDHPPT | ALDH1A1 2382/4885CYP3A4 208/4885MAPT 3015/4885 |
| US-20130204041-A1 | 2,4,5-TRIAMINOPHENOLS AND RELATED COMPOUNDS | WDR48, AADAC, DDX41 | ALDH1A1 1701/4885CYP3A4 224/4885MAPT 284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.