Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16804882 | 0.81 | ALDH1A1 (0.64) | MAPTALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL5545979 | 0.77 | ALDH1A1 (0.65) | MAPTALDH1A1POLBLMNASMN1; SMN2 | |
| Toluene SCHEMBL27898610 | 0.77 | ALDH1A1 (0.49) | MAPTALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL7896507 | 0.76 | MAPT (0.64) | MAPTALDH1A1POLBLMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7888531 | 0.76 | MAPT (0.57) | MAPTALDH1A1POLBLMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7895987 | 0.76 | MAPT (0.63) | MAPTALDH1A1POLBLMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7896677 | 0.75 | MAPT (0.62) | MAPTALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL10199973 | 0.74 | MAPT (0.56) | MAPTALDH1A1POLBLMNASMN1; SMN2 | |
| Isophthalic Acid SCHEMBL27822644 | 0.74 | KMT2A (0.50) | MAPTALDH1A1POLBLMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7898969 | 0.72 | MAPT (0.58) | MAPTALDH1A1POLBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150164910-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150164910-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF USE | EIF2AK2, RNASE1, HAVCR2 | MAPT 4474/4885ALDH1A1 4417/4885POLB 256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.