Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | ATM | Q13315 | 3/20 | 0.54 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.54 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7895987 | 0.85 | MAPT (0.63) | ALDH1A1MAPTPOLBSMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL7896677 | 0.82 | MAPT (0.62) | ALDH1A1MAPTPOLBSMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL7898969 | 0.81 | MAPT (0.58) | ALDH1A1MAPTPOLBSMN1; SMN2KMT2A | |
| SCHEMBL7896507 | 0.80 | MAPT (0.64) | ALDH1A1MAPTPOLBSMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL7888531 | 0.80 | MAPT (0.57) | ALDH1A1MAPTPOLBSMN1; SMN2KMT2A | |
| SCHEMBL29957640 | 0.80 | KMT2A (0.72) | ALDH1A1MAPTPOLBKMT2AGAA | |
| SCHEMBL29955086 | 0.78 | KCNQ2 (0.74) | POLBKMT2AGAAKCNQ2PKM | |
| SCHEMBL29957211 | 0.78 | KMT2A (0.68) | ALDH1A1MAPTPOLBSMN1; SMN2KMT2A | |
| SCHEMBL1479354 | 0.78 | ADRA1A (0.58) | ALDH1A1MAPTPOLBSMN1; SMN2KMT2A | |
| SCHEMBL16783142 | 0.77 | MAPT (0.63) | ALDH1A1MAPTPOLBSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070135499-A1 | Hydrazide compounds | AERIE PHARMACEUTICALS, INC. (US) | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135499-A1 | Hydrazide compounds | GRK4, GRK2, GRK1 | ALDH1A1 2861/4885MAPT 3473/4885POLB 4298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.