SCHEMBL167845

SCHEMBL167845

NOC(=O)[C@@H](N)CCC(N)=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.58
BLM P54132 1/20 0.58
PMP22 Q01453 1/20 0.58
KMT2A Q03164 1/20 0.58
DPP4 P27487 1/20 0.42
DPP8 Q6V1X1 1/20 0.42
DPP9 Q86TI2 1/20 0.42
GRM8 O00222 1/20 0.38
GRM6 O15303 1/20 0.38
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38
GSR P00390 1/20 0.38
CYP1A2 P05177 1/20 0.38
GRIK1 P39086 1/20 0.38
GRM5 P41594 1/20 0.38
GRIA1 P42261 1/20 0.38
GRIA2 P42262 1/20 0.38
GRIA3 P42263 1/20 0.38
SLC1A3 P43003 1/20 0.38
SLC1A2 P43004 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16200626 0.89 KMT2A (0.45) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL711607 0.88 ALOX15 (0.60) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL7451576 0.85 ALOX15 (0.47) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL7176759 0.84 ALOX15 (0.56) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL8610972 0.83 ALOX15 (0.59) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL28809039 0.82 ALOX15 (0.48) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL1577692 0.82 ALOX15 (0.58) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL22502695 0.82 GRM8 (0.60) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL1373976 0.82 SLC1A1 (0.38) ALOX15BLMPMP22KMT2AGRM8
SCHEMBL5496875 0.82 GRM8 (0.60) ALOX15BLMPMP22KMT2ADPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 447 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240138433-A1 PLANT-BASED INTRAMUSCULAR FAT SUBSTITUTES BUNGE SA (CH) 2024-05-02 US claimed
EP-4294198-A1 PLANT-BASED INTRAMUSCULAR FAT SUBSTITUTES Bunge SA (CH) 2023-12-27 EP claimed
CN-117156975-A Plant-based intramuscular fat substitutes 邦吉SA公司 2023-12-01 CN claimed
WO-2022177943-A1 PLANT-BASED INTRAMUSCULAR FAT SUBSTITUTES BUNGE NORTH AMERICA, INC. (US) 2022-08-25 WO claimed
EP-3570875-B1 PEPTIDE MODULATORS OF THE INTERACTION BETWEEN HUMAN C-PEPTIDE AND HUMAN ELASTIN RECEPTOR FOR THERAPEUTIC USE BIOTEMPT BV (NL) 2022-07-06 EP claimed
CN-111164238-B Device for reversible photoelectrochemical water splitting using a bacteriorhodopsin-sensitized photoelectrode 质子新能源未来公司 2022-04-19 CN claimed
EP-3390440-B1 C-TERMINAL LYSINE CONJUGATED IMMUNOGLOBULINS EISAI R&D MAN CO LTD (JP) 2022-02-02 EP claimed
EP-3694536-A2 A CELL-BASED SEEDING ASSAY FOR HUNTINGTIN AGGREGATION The Regents of The University of California (US) 2020-08-19 EP claimed
US-20200255487-A1 A Cell-Based Seeding Assay for Huntingtin Aggregation THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-08-13 US claimed
EP-3465221-B1 BIOANALYTICAL METHOD FOR THE CHARACTERIZATION OF SITE-SPECIFIC ANTIBODY-DRUG CONJUGATES HOFFMANN LA ROCHE (CH) 2020-07-22 EP claimed
JP-3822231-B2 2006-09-13 JP claimed
EP-0662122-B1 IMPROVED ENZYMES FOR THE PRODUCTION OF 2-KETO-L-GULONIC ACID UNIV RUTGERS (US) 2004-06-09 EP claimed
US-20020045231-A1 Catalytic antibodies which hydrolyze primary amides and methods for eliciting such antibodies WELLSTAT BIOCATALYSIS, LLC 2002-04-18 US claimed
EP-0807691-B1 A method for screening for the presence of a genetic defect associated with thrombosis and/or poor anticoagulant response to activated protein C. UNIV LEIDEN (NL) 2001-10-10 EP claimed
EP-0696318-A4 CATALYTIC ANTIBODIES WHICH HYDROLYZE PRIMARY AMIDES AND METHODS FOR ELICITING SUCH ANTIBODIES IGEN INC (US) 1998-04-15 EP claimed
EP-0696318-A1 CATALYTIC ANTIBODIES WHICH HYDROLYZE PRIMARY AMIDES AND METHODS FOR ELICITING SUCH ANTIBODIES IGEN, INC. (a California corporation) (US) 1996-02-14 EP claimed
WO-1994025573-A1 CATALYTIC ANTIBODIES WHICH HYDROLYZE PRIMARY AMIDES AND METHODS FOR ELICITING SUCH ANTIBODIES IGEN, INC. (US) 1994-11-10 WO claimed
CN-1093701-A Antiretroviral hydrazine derivative CIBA GEIGY AG (CH) 1994-10-19 CN claimed
EP-0359338-B1 Peptide compounds HAFSLUND NYCOMED AS (NO) 1994-08-31 EP claimed
US-4642118-A Man-made skin composed of two layers: collagen and a poly-alpha-amino acid KOKEN CO., LTD. (JP) 1987-02-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020045231-A1 Catalytic antibodies which hydrolyze primary amides and methods for eliciting such antibodies AMY1A, AMY2A, HRH2 ALOX15 409/4885BLM 2206/4885PMP22 966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.