Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 3/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16776392 | 0.90 | SLC5A1 (0.34) | SLC5A1GRIN1GRIN2B | |
| SCHEMBL16775999 | 0.74 | ADORA2A (0.36) | SLC5A1CTSKKCNH2 | |
| SCHEMBL16776347 | 0.73 | ALOX15 (0.38) | SLC5A1GRIN1GRIN2B | |
| SCHEMBL16785583 | 0.72 | FAAH (0.38) | — | |
| SCHEMBL16785644 | 0.72 | TSHR (0.46) | — | |
| SCHEMBL16776038 | 0.69 | CNR1 (0.36) | — | |
| SCHEMBL16776366 | 0.68 | PHGDH (0.40) | SLC5A1 | |
| SCHEMBL16776360 | 0.68 | HTR2C (0.46) | — | |
| SCHEMBL16776216 | 0.68 | ABL1 (0.34) | — | |
| SCHEMBL16776365 | 0.67 | MPL (0.43) | SLC5A1GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150152108-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE LLC | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152108-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | SIRT1, SIRT3, SIRT2 | SLC5A1 1202/4885GRIN1 4373/4885GRIN2B 4510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.