SCHEMBL167861

SCHEMBL167861

O=S(=O)(OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CA2 P00918 16/20 0.48
▸ CA1 P00915 15/20 0.46
▸ MMP1 P03956 5/20 0.46
▸ MMP2 P08253 5/20 0.46
▸ MMP9 P14780 5/20 0.46
▸ MMP8 P22894 5/20 0.46
▸ MMP13 P45452 5/20 0.46
▸ F2 P00734 4/20 0.41
▸ PRSS1 P07477 4/20 0.41
▸ PRSS2 P07478 4/20 0.41
▸ PRSS3 P35030 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16444987 0.97 CA2 (0.52) CA2CA1MMP1MMP2MMP9
SCHEMBL6396150 0.97 CA2 (0.52) CA2CA1MMP1MMP2MMP9
SCHEMBL1146256 0.97 CA2 (0.52) CA2CA1MMP1MMP2MMP9
SCHEMBL11806270 0.97 CA2 (0.52) CA2CA1MMP1MMP2MMP9
SCHEMBL3960813 0.97 CA2 (0.52) CA2CA1MMP1MMP2MMP9
SCHEMBL8108242 0.97 CA2 (0.52) CA2CA1MMP1MMP2MMP9
SCHEMBL11802495 0.97 CA2 (0.52) CA2CA1MMP1MMP2MMP9
SCHEMBL11810378 0.97 CA2 (0.52) CA2CA1MMP1MMP2MMP9
SCHEMBL8437170 0.97 CA2 (0.52) CA2CA1MMP1MMP2MMP9
SCHEMBL5078467 0.97 CA2 (0.52) CA2CA1MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 360 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120081755-A Process for preparing 3- (4' -aminophenyl) -2-methoxypropionic acid and analogues and intermediates thereof 诺格拉制药有限公司 2025-06-03 — — CN claimed
CN-113825739-B Process for preparing 3- (4' -aminophenyl) -2-methoxypropionic acid and analogues and intermediates thereof 诺格拉制药有限公司 2025-03-28 — — CN claimed
CN-119661433-A Photoacid generator, preparation method thereof and photoresist based on photoacid generator 徐州博康信息化学品有限公司 2025-03-21 — — CN claimed
EP-4511372-A1 PROCESSES AND INTERMEDIATES FOR SYNTHESIS OF ADAGRASIB Mirati Therapeutics, Inc. (US) 2025-02-26 — — EP claimed
EP-4495101-A2 PROCESS OF MAKING 3-(4'-AMINOPHENYL)-2-METHOXYPROPIONIC ACID, AND ANALOGS AND INTERMEDIATES THEREOF Nogra Pharma Limited (IE) 2025-01-22 — — EP claimed
US-20240409498-A1 PROCESS OF MAKING 3-(4'-AMINOPHENYL)-2-METHOXYPROPIONIC ACID, AND ANALOGS AND INTERMEDIATES THEREOF NOGRA PHARMA LIMITED (IE) 2024-12-12 — — US claimed
CN-119072477-A Process and intermediates for the synthesis of adaglazeb 米拉蒂治疗股份有限公司 2024-12-03 — — CN claimed
EP-3921299-B1 PROCESS OF MAKING 3-(4'-AMINOPHENYL)-2-METHOXYPROPIONIC ACID, AND ANALOGS AND INTERMEDIATES THEREOF NOGRA PHARMA LTD (IE) 2024-11-20 — — EP claimed
CN-111848832-B Application of fluorine-containing compound modified cationic polymer as drug carrier and preparation method thereof 苏州大学 2024-02-20 — — CN claimed
WO-2023205074-A1 PROCESSES AND INTERMEDIATES FOR SYNTHESIS OF ADAGRASIB Mirati Therapeutics, Inc. (US) 2023-10-26 — — WO claimed
US-20220194894-A1 PROCESS OF MAKING 3-(4'-AMINOPHENYL)-2-METHOXYPROPIONIC ACID, AND ANALOGS AND INTERMEDIATES THEREOF NOGRA PHARMA LIMITED (IE) 2022-06-23 — — US claimed
CN-113825739-A Process for preparing 3- (4' -aminophenyl) -2-methoxypropionic acid and analogs and intermediates thereof 诺格拉制药有限公司 2021-12-21 — — CN claimed
CN-106458903-B Method for producing heteroaromatic sulfonamide compound 宇部兴产株式会社 2021-02-05 — — CN claimed
WO-2020132057-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH ANHYDRIDE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION (US) 2020-06-25 — — WO claimed
US-20200203711-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH ANHYDRIDE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2020-06-25 — — US claimed
CN-110556509-A Method for performing surface protection and passivation treatment on metallic lithium cathode by using fluorine-containing organic matter, product and application NANJING UNIVERSITY OF TECHNOLOGY 2019-12-10 — — CN claimed
EP-3156395-B1 METHOD FOR PRODUCING HETEROAROMATIC SULFONAMIDE COMPOUND UBE INDUSTRIES (JP) 2019-01-09 — — EP claimed
US-20170121288-A1 METHOD FOR PRODUCING HETEROAROMATIC SULFONAMIDE COMPOUND UBE INDUSTRIES, LTD. (JP) 2017-05-04 — — US claimed
EP-3156395-A1 METHOD FOR PRODUCING HETEROAROMATIC SULFONAMIDE COMPOUND UBE Industries, Ltd. (JP) 2017-04-19 — — EP claimed
US-5380789-A Punching HITACHI CHEMICAL COMPANY, LTD. (JP) 1995-01-10 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220194894-A1 PROCESS OF MAKING 3-(4'-AMINOPHENYL)-2-METHOXYPROPIONIC ACID, AND ANALOGS AND INTERMEDIATES THEREOF PPARA, PPARG, PPARD CA2 4023/4885CA1 4808/4885MMP1 4783/4885
US-20170121288-A1 METHOD FOR PRODUCING HETEROAROMATIC SULFONAMIDE COMPOUND PFAS, SULT2A1, ARSA CA2 102/4885CA1 62/4885MMP1 3889/4885
US-20240409498-A1 PROCESS OF MAKING 3-(4'-AMINOPHENYL)-2-METHOXYPROPIONIC ACID, AND ANALOGS AND INTERMEDIATES THEREOF PPARA, PPARG, PPARD CA2 3836/4885CA1 4747/4885MMP1 4826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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