Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29558509 | 1.00 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2POLBKDM4E | |
| SCHEMBL28681971 | 0.95 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2POLBKDM4E | |
| SCHEMBL29251789 | 0.86 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2POLBKDM4E | |
| SCHEMBL21523381 | 0.84 | ALDH1A1 (0.54) | NPC1RAB9ASMN1; SMN2POLBKDM4E | |
| SCHEMBL29252043 | 0.83 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2POLBKDM4E | |
| SCHEMBL29251927 | 0.83 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2POLBKDM4E | |
| SCHEMBL29251600 | 0.82 | PSIP1 (0.33) | NPC1RAB9ASMN1; SMN2POLBKDM4E | |
| SCHEMBL29559022 | 0.82 | SMN1; SMN2 (0.61) | NPC1RAB9ASMN1; SMN2POLBKDM4E | |
| SCHEMBL9171403 | 0.82 | SMN1; SMN2 (0.61) | NPC1RAB9ASMN1; SMN2POLBKDM4E | |
| SCHEMBL12558659 | 0.81 | NPC1 (0.37) | NPC1RAB9ASMN1; SMN2POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114262917-A | Electrolytic nickel (alloy) plating solution | 日本高纯度化学株式会社 | 2022-04-01 | — | — | CN | claimed |
| CN-114262917-A | Electrolytic nickel (alloy) plating solution | 日本高纯度化学株式会社 | 2022-04-01 | — | — | CN | disclosed |
| CN-109996907-B | Electrolytic nickel (alloy) plating solution | 日本高纯度化学株式会社 | 2022-01-11 | — | — | CN | disclosed |
| US-20170281662-A1 | POLYCARBONATES BEARING AROMATIC N-HETEROCYCLES FOR DRUG DELIVERY | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2017-10-05 | — | — | US | disclosed |
| US-9717797-B2 | Polycarbonates bearing aromatic N-heterocycles for drug delivery | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2017-08-01 | — | — | US | disclosed |
| US-9717797-B2 | Polycarbonates bearing aromatic N-heterocycles for drug delivery | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2017-08-01 | — | — | US | disclosed |
| US-20150157723-A1 | POLYCARBONATES BEARING AROMATIC N-HETEROCYCLES FOR DRUG DELIVERY | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-06-11 | — | — | US | disclosed |
| US-20150157723-A1 | POLYCARBONATES BEARING AROMATIC N-HETEROCYCLES FOR DRUG DELIVERY | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150157723-A1 | POLYCARBONATES BEARING AROMATIC N-HETEROCYCLES FOR DRUG DELIVERY | PAH, SULT1E1, SULT1A1 | NPC1 3216/4885RAB9A 2497/4885SMN1; SMN2 1927/4885 |
| US-20170281662-A1 | POLYCARBONATES BEARING AROMATIC N-HETEROCYCLES FOR DRUG DELIVERY | PAH, SULT1E1, SULT1A1 | NPC1 3216/4885RAB9A 2497/4885SMN1; SMN2 1927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.