Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 5/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 8/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 8/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4942777 | 0.82 | NR1H2 (0.53) | NR1H2NR1H3MRGPRX4FFAR4FFAR1 | |
| SCHEMBL1678705 | 0.82 | NR1H2 (0.43) | NR1H2NR1H3AKR1C3AKR1C2MRGPRX4 | |
| SCHEMBL1679125 | 0.81 | NR1H2 (0.38) | NR1H2NR1H3AKR1C3AKR1C2CYP2C19 | |
| SCHEMBL1678766 | 0.76 | AKR1C3 (0.50) | NR1H2NR1H3AKR1C3AKR1C2CYP2C19 | |
| SCHEMBL1679159 | 0.75 | AKR1C3 (0.49) | NR1H2NR1H3AKR1C3AKR1C2CYP2C19 | |
| SCHEMBL1679138 | 0.73 | CYP2C19 (0.52) | NR1H2NR1H3AKR1C3AKR1C2CYP2C19 | |
| SCHEMBL1679399 | 0.71 | NR1H2 (0.37) | NR1H2NR1H3AKR1C3AKR1C2CYP2C19 | |
| SCHEMBL4938650 | 0.70 | NR1H2 (0.58) | NR1H2NR1H3FFAR4FFAR1 | |
| SCHEMBL1679283 | 0.70 | NR1H2 (0.51) | NR1H2NR1H3AKR1C3AKR1C2AKR1C4 | |
| SCHEMBL4944371 | 0.70 | NR1H2 (0.53) | NR1H2NR1H3FFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7923573-B2 | Benzene compound having 2 or more substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-04-12 | — | — | US | disclosed |