Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 5/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.51 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1678766 | 0.86 | AKR1C3 (0.50) | NR1H2NR1H3ADAMTS4MMP13AKR1C3 | |
| SCHEMBL1679159 | 0.85 | AKR1C3 (0.49) | NR1H2NR1H3ADAMTS4MMP13AKR1C3 | |
| SCHEMBL4942716 | 0.82 | NR1H2 (0.70) | NR1H2NR1H3FFAR1RXRAPTGER4 | |
| SCHEMBL1678648 | 0.79 | NR1H2 (0.42) | NR1H2NR1H3ADAMTS4MMP13AKR1C3 | |
| SCHEMBL1678906 | 0.76 | ADAMTS4 (0.41) | NR1H2NR1H3ADAMTS4MMP13AKR1C3 | |
| SCHEMBL4944371 | 0.74 | NR1H2 (0.53) | NR1H2NR1H3FFAR1RXRA | |
| SCHEMBL1678343 | 0.74 | NR1H2 (0.72) | NR1H2NR1H3ADAMTS4MMP13AKR1C3 | |
| SCHEMBL4938650 | 0.73 | NR1H2 (0.58) | NR1H2NR1H3FFAR1RXRA | |
| SCHEMBL31261551 | 0.72 | PTGS2 (0.64) | AKR1C3AKR1C2FFAR1RXRAPTGS2 | |
| SCHEMBL1679556 | 0.72 | NR1H2 (0.58) | NR1H2NR1H3ADAMTS4MMP13FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7923573-B2 | Benzene compound having 2 or more substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-04-12 | — | — | US | disclosed |