Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 6/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 9/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 9/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.34 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4946640 | 0.84 | NR1H2 (0.45) | NR1H2NR1H3MRGPRX4FFAR4 | |
| SCHEMBL1679523 | 0.83 | NR1H2 (0.37) | NR1H2NR1H3AKR1C3AKR1C2AKR1B10 | |
| SCHEMBL1678615 | 0.82 | NR1H2 (0.44) | NR1H2NR1H3AKR1C3AKR1C2AKR1B10 | |
| SCHEMBL1678810 | 0.81 | NR1H2 (0.35) | NR1H2NR1H3AKR1C3AKR1C2AKR1B10 | |
| SCHEMBL1678818 | 0.79 | APP (0.47) | AKR1C3AKR1C2AKR1C4AKR1C1APP | |
| SCHEMBL1678703 | 0.77 | ADAMTS4 (0.41) | NR1H2NR1H3AKR1C3AKR1C2AKR1C4 | |
| SCHEMBL4945301 | 0.75 | NR1H2 (0.45) | NR1H2NR1H3FFAR4 | |
| SCHEMBL1678648 | 0.73 | NR1H2 (0.42) | NR1H2NR1H3AKR1C3AKR1C2AKR1C4 | |
| SCHEMBL4938686 | 0.72 | NR1H2 (0.55) | NR1H2NR1H3 | |
| SCHEMBL4942432 | 0.71 | NR1H2 (0.44) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7923573-B2 | Benzene compound having 2 or more substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-04-12 | — | — | US | disclosed |