Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ESRRA | P11474 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 2/20 | 0.30 |
| ▸ | RXRB | P28702 | 2/20 | 0.30 |
| ▸ | RXRG | P48443 | 2/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1678810 | 0.86 | NR1H2 (0.35) | NR1H2NR1H3FFAR1AKR1C3AKR1C2 | |
| SCHEMBL4940004 | 0.83 | RXRA (0.48) | NR1H2NR1H3FFAR1RXRARXRB | |
| SCHEMBL1678705 | 0.83 | NR1H2 (0.43) | NR1H2NR1H3AKR1C3AKR1C2AKR1B10 | |
| SCHEMBL1679125 | 0.81 | NR1H2 (0.38) | NR1H2NR1H3FFAR1AKR1C3AKR1C2 | |
| SCHEMBL1679399 | 0.80 | NR1H2 (0.37) | NR1H2NR1H3FFAR1AKR1C3AKR1C2 | |
| SCHEMBL4942432 | 0.76 | NR1H2 (0.44) | NR1H2NR1H3FFAR1RXRARXRB | |
| SCHEMBL1678703 | 0.75 | ADAMTS4 (0.41) | NR1H2NR1H3FFAR1AKR1C3AKR1C2 | |
| SCHEMBL1678818 | 0.73 | APP (0.47) | AKR1C3AKR1C2AKR1C4AKR1C1CYP2C19 | |
| SCHEMBL1678648 | 0.73 | NR1H2 (0.42) | NR1H2NR1H3FFAR1AKR1C3AKR1C2 | |
| SCHEMBL4938686 | 0.70 | NR1H2 (0.55) | NR1H2NR1H3FFAR1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7923573-B2 | Benzene compound having 2 or more substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-04-12 | — | — | US | disclosed |