Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 9/20 | 0.50 |
| ▸ | PPARD | Q03181 | 5/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15293871 | 0.89 | DGAT1 (0.62) | DGAT1PPARDALOX5APFEN1MAPT | |
| SCHEMBL21838857 | 0.80 | DGAT1 (0.41) | DGAT1TP53MAPTKDM4ENPC1 | |
| SCHEMBL23797464 | 0.76 | DGAT1 (0.44) | DGAT1PPARDALOX5APFEN1MAPT | |
| SCHEMBL21838852 | 0.74 | DGAT1 (0.42) | DGAT1TP53MAPTKDM4ENPC1 | |
| SCHEMBL16660926 | 0.74 | DGAT1 (0.49) | DGAT1ALOX5APFEN1TP53MAPT | |
| SCHEMBL9936783 | 0.73 | DGAT1 (0.77) | DGAT1KDM4E | |
| SCHEMBL15019899 | 0.72 | MAPT (0.42) | MAPTKDM4ENPC1 | |
| SCHEMBL31079139 | 0.72 | DGAT1 (0.47) | DGAT1PPARDALOX5APFEN1MAPT | |
| SCHEMBL16277767 | 0.71 | DGAT1 (0.39) | DGAT1MAPTNPC1 | |
| SCHEMBL66909 | 0.71 | DGAT1 (0.47) | DGAT1PPARDALOX5APFEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150158844-A1 | AROMATIC HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-06-11 | — | — | US | disclosed |
| US-20150158844-A1 | AROMATIC HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150158844-A1 | AROMATIC HETEROCYCLIC COMPOUND | GPR119, NR0B1, BET1 | DGAT1 1688/4885PPARD 471/4885ALOX5AP 3627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.