Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.31 |
| ▸ | MLNR | O43193 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17132313 | 0.82 | BBOX1 (0.32) | BBOX1 | |
| SCHEMBL1864397 | 0.81 | DNM1 (0.48) | BBOX1HTTDNM1APPENPP2 | |
| SCHEMBL15382997 | 0.81 | DNM1 (0.50) | BBOX1HTTDNM1APPENPP2 | |
| SCHEMBL918271 | 0.81 | BBOX1 (0.46) | BBOX1HTTDNM1APPLMNA | |
| SCHEMBL12715630 | 0.80 | BBOX1 (0.37) | BBOX1APP | |
| SCHEMBL12936200 | 0.80 | HSD17B10 (0.32) | DNM1APPHSD17B10 | |
| SCHEMBL11504754 | 0.80 | HTT (0.48) | HTTDNM1MLNRNR1I2ESR1 | |
| SCHEMBL11504766 | 0.80 | HTT (0.48) | HTTDNM1MLNRNR1I2ESR1 | |
| SCHEMBL11505834 | 0.80 | HTT (0.48) | HTTDNM1MLNRNR1I2ESR1 | |
| Water SCHEMBL1271206 | 0.80 | DNM1 (0.46) | BBOX1HTTDNM1APPENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9410958-B2 | Alkyne-activated fluorogenic azide compounds and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-08-09 | — | — | US | disclosed |
| US-9249379-B2 | Liquid laundry detergent | CONOPCO, INC. (US) | 2016-02-02 | — | — | US | disclosed |
| US-20150276752-A1 | ALKYNE-ACTIVATED FLUOROGENIC AZIDE COMPOUNDS AND METHODS OF USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-10-01 | — | — | US | disclosed |
| US-20150159121-A1 | LIQUID LAUNDRY DETERGENT | CONOPCO, INC., D/B/A UNILEVER | 2015-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150276752-A1 | ALKYNE-ACTIVATED FLUOROGENIC AZIDE COMPOUNDS AND METHODS OF USE THEREOF | ALK, DNPEP, ACR | BBOX1 987/4885HTT 1311/4885DNM1 2265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.