SCHEMBL16790504

SCHEMBL16790504

CC(C)(C)OC(=O)Oc1c(C(C)(C)C)cc(CCC(=O)OCC(COC(=O)CCc2cc(C(C)(C)C)c(OC(=O)OC(C)(C)C)c(C(C)(C)C)c2)(COC(=O)CCc2cc(C(C)(C)C)c(OC(=O)OC(C)(C)C)c(C(C)(C)C)c2)COC(=O)CCc2cc(C(C)(C)C)c(OC(=O)OC(C)(C)C)c(C(C)(C)C)c2)cc1C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ VCAM1 P19320 11/20 0.38
▸ GAA P10253 3/20 0.37
▸ KMT2A Q03164 2/20 0.35
▸ ELANE P08246 1/20 0.33
▸ MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22678399 0.94 VCAM1 (0.35) VCAM1GAAKMT2A
SCHEMBL17171782 0.90 VCAM1 (0.33) VCAM1GAAKMT2A
SCHEMBL17171730 0.90 CYP4F2 (0.43) VCAM1GAAKMT2A
SCHEMBL17171726 0.89 VCAM1 (0.38) VCAM1GAAKMT2A
SCHEMBL17546542 0.88 GAA (0.39) VCAM1GAAKMT2A
SCHEMBL17171727 0.88 VCAM1 (0.39) VCAM1GAAKMT2A
SCHEMBL17546561 0.87 VCAM1 (0.35) VCAM1GAAKMT2A
SCHEMBL17171725 0.87 VCAM1 (0.51) VCAM1GAAKMT2AMEN1
SCHEMBL19103204 0.86 VCAM1 (0.36) VCAM1GAAKMT2A
SCHEMBL19103203 0.85 VCAM1 (0.38) VCAM1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2881450-B1 LATENT ADDITIVE AND COMPOSITION CONTAINING LATENT ADDITIVE ADEKA CORP (JP) 2020-09-09 — — EP disclosed
US-9777138-B2 Latent additive and composition containing latent additive ADEKA CORPORATION (JP) 2017-10-03 — — US disclosed
US-9777138-B2 Latent additive and composition containing latent additive ADEKA CORPORATION (JP) 2017-10-03 — — US disclosed
US-20170198117-A1 ANTIOXIDANT FOR THERMOPLASTIC RESIN AND THERMOPLASTIC RESIN COMPOSITION CONTAINING SAME ADEKA CORPORATION (JP) 2017-07-13 — — US disclosed
US-20170198117-A1 ANTIOXIDANT FOR THERMOPLASTIC RESIN AND THERMOPLASTIC RESIN COMPOSITION CONTAINING SAME ADEKA CORPORATION (JP) 2017-07-13 — — US disclosed
WO-2017030005-A1 COMPOSITION 株式会社ADEKA 2017-02-23 — — WO disclosed
WO-2016021315-A1 ANTIOXIDANT FOR THERMOPLASTIC RESIN AND THERMOPLASTIC RESIN COMPOSITION INCLUDING SAME 株式会社ADEKA 2016-02-11 — — WO disclosed
US-20150291772-A1 LATENT ADDITIVE AND COMPOSITION CONTAINING LATENT ADDITIVE ADEKA CORPORATION (JP) 2015-10-15 — — US disclosed
US-20150291772-A1 LATENT ADDITIVE AND COMPOSITION CONTAINING LATENT ADDITIVE ADEKA CORPORATION (JP) 2015-10-15 — — US disclosed
EP-2881450-A1 LATENT ADDITIVE AND COMPOSITION CONTAINING LATENT ADDITIVE Adeka Corporation (JP) 2015-06-10 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150291772-A1 LATENT ADDITIVE AND COMPOSITION CONTAINING LATENT ADDITIVE TCF7L2, LUC7L2, TLL2 VCAM1 4699/4885GAA 2583/4885KMT2A 2013/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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