SCHEMBL16790748

SCHEMBL16790748

CC(=O)[C@H](CCCCNC(=O)CI)NC(=O)CI

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALB P02768 3/20 0.42
FOLH1 Q04609 9/20 0.41
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
SIRT6 Q8N6T7 1/20 0.39
SIRT1 Q96EB6 1/20 0.39
SIRT5 Q9NXA8 2/20 0.37
KDM4E B2RXH2 1/20 0.36
MAPK1 P28482 1/20 0.36
HIF1A Q16665 1/20 0.36
NOD1 Q9Y239 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16790734 0.88 ALB (0.38) ALBFOLH1MEN1KMT2ASIRT6
SCHEMBL20528861 0.84 FOLH1 (0.49) ALBFOLH1NOD1
SCHEMBL20528860 0.84 FOLH1 (0.49) ALBFOLH1NOD1
SCHEMBL16790731 0.83 MEN1 (0.46) ALBFOLH1MEN1KMT2ASIRT6
SCHEMBL16790769 0.83 SMN1; SMN2 (0.53) ALBFOLH1MEN1KMT2ASIRT6
SCHEMBL13402312 0.83 MEN1 (0.59) ALBFOLH1MEN1KMT2ASIRT6
SCHEMBL19069723 0.82 ALB (0.58) ALBFOLH1SIRT6SIRT1KDM4E
SCHEMBL19441342 0.82 MEN1 (0.36) ALBFOLH1MEN1KMT2ASIRT6
SCHEMBL16093456 0.81 FOLH1 (0.50) ALBFOLH1MEN1KMT2ASIRT6
SCHEMBL26053493 0.81 FOLH1 (0.38) ALBFOLH1MEN1KMT2ASIRT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9783571-B2 Isolation of cysteine containing peptides MARTIN WARHAM LANCE (US) 2017-10-10 US disclosed
US-20150158905-A1 Isolation of Cysteine Containing Peptides MARTIN WARHAM LANCE (US) 2015-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150158905-A1 Isolation of Cysteine Containing Peptides LNPEP, CSTB, CPB1 ALB 765/4885FOLH1 59/4885MEN1 3253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.