SCHEMBL20528860

SCHEMBL20528860

O=C(CI)NCCCC[C@H](NC(=O)CI)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 17/20 0.49
ALB P02768 2/20 0.47
NOD1 Q9Y239 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20528861 1.00 FOLH1 (0.49) FOLH1ALBNOD1
SCHEMBL19069723 0.90 ALB (0.58) FOLH1ALB
SCHEMBL23129208 0.88 NOD1 (0.52) FOLH1NOD1
SCHEMBL15871482 0.86 FOLH1 (0.43) FOLH1ALBNOD1
SCHEMBL14729288 0.86 FOLH1 (0.70) FOLH1
SCHEMBL16790748 0.84 ALB (0.42) FOLH1ALBNOD1
SCHEMBL18889449 0.84 NOD1 (0.67) FOLH1NOD1
SCHEMBL30905812 0.84 NOD1 (0.64) FOLH1NOD1
SCHEMBL20528853 0.82 SMN1; SMN2 (0.55) FOLH1ALBNOD1
SCHEMBL20528854 0.82 SMN1; SMN2 (0.55) FOLH1ALBNOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11471537-B2 Oligomer extended insulin-Fc conjugates NOVO NORDISK A/S (DK) 2022-10-18 US disclosed
US-20200261595-A1 Oligomer Extended Insulin-FC Conjugates NOVO NORDISK A/S (DK) 2020-08-20 US disclosed
EP-3606560-A2 OLIGOMER EXTENDED INSULIN-FC CONJUGATES Novo Nordisk A/S (DK) 2020-02-12 EP disclosed
WO-2018185131-A2 OLIGOMER EXTENDED INSULIN-FC CONJUGATES NOVO NORDISK A/S (DK) 2018-10-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200261595-A1 Oligomer Extended Insulin-FC Conjugates IAPP, IDE, INSR FOLH1 1170/4885ALB 213/4885NOD1 401/4885
US-11471537-B2 Oligomer extended insulin-Fc conjugates IAPP, IDE, INSR FOLH1 1170/4885ALB 213/4885NOD1 401/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.