Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP3 | P08254 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | MMP12 | P39900 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | MMP14 | P50281 | 1/20 | 0.55 |
| ▸ | MMP16 | P51512 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 6/20 | 0.44 |
| ▸ | PPARG | P37231 | 5/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679149 | 0.83 | CYP2C9 (0.48) | MMP2MMP3MMP9MMP8MMP12 | |
| SCHEMBL13366078 | 0.83 | ABL1 (0.47) | APPBACE1SMN1; SMN2HDAC4HDAC2 | |
| SCHEMBL1679330 | 0.82 | APP (0.49) | MMP2MMP3MMP9MMP8MMP12 | |
| SCHEMBL1679633 | 0.78 | CYP2C19 (0.54) | MMP2MMP3MMP9MMP8MMP12 | |
| SCHEMBL2744891 | 0.77 | SMN1; SMN2 (0.59) | CYP2C19SMN1; SMN2HDAC4HDAC2HDAC8 | |
| SCHEMBL15743720 | 0.77 | ABL1 (0.59) | APPBACE1SMN1; SMN2HDAC4HDAC2 | |
| SCHEMBL28518787 | 0.76 | PTGS1 (0.46) | SMN1; SMN2PTGS2PTGS1 | |
| SCHEMBL1678823 | 0.75 | PDE4A (0.45) | MMP2MMP3MMP9MMP8MMP12 | |
| SCHEMBL3954798 | 0.74 | PTGS2 (0.55) | MMP2MMP3MMP9MMP8MMP12 | |
| SCHEMBL4941492 | 0.73 | MMP2 (0.58) | MMP2MMP3MMP9MMP8MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7923573-B2 | Benzene compound having 2 or more substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-04-12 | — | — | US | disclosed |