Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 12/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 12/20 | 0.51 |
| ▸ | APLNR | P35414 | 4/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | FABP2 | P12104 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27747528 | 0.87 | APLNR (0.48) | PTGS1PTGS2APLNRDGAT1FPR2 | |
| SCHEMBL18839300 | 0.84 | DGAT1 (0.51) | PTGS1PTGS2APLNRDGAT1FPR2 | |
| SCHEMBL14274718 | 0.83 | APLNR (0.44) | PTGS1PTGS2APLNRDGAT1FPR2 | |
| SCHEMBL19182930 | 0.81 | PTGS1 (0.54) | PTGS1PTGS2MEN1FABP2TSHR | |
| SCHEMBL31117279 | 0.81 | PTGS1 (0.54) | PTGS1PTGS2MEN1FABP2TSHR | |
| SCHEMBL19182931 | 0.81 | PTGS1 (0.54) | PTGS1PTGS2MEN1FABP2TSHR | |
| SCHEMBL2130305 | 0.81 | APLNR (0.50) | PTGS1PTGS2APLNRDGAT1FPR2 | |
| SCHEMBL16219361 | 0.80 | PTGS1 (0.52) | PTGS1PTGS2MEN1FABP2TSHR | |
| SCHEMBL16207512 | 0.80 | PTGS2 (0.52) | PTGS1PTGS2MEN1FABP2TSHR | |
| SCHEMBL8157598 | 0.80 | GRM1 (0.41) | PTGS1PTGS2FPR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101039-A1 | CALCIUM-SENSING RECEPTOR-ACTIVE COMPOUNDS | LEO PHARMA A/S (DK) | 2012-04-26 | — | — | US | disclosed |
| US-7923573-B2 | Benzene compound having 2 or more substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-04-12 | — | — | US | disclosed |
| WO-2010136036-A2 | CALCIUM-SENSING RECEPTOR-ACTIVE COMPOUNDS | LEO PHARMA A/S (DK) | 2010-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101039-A1 | CALCIUM-SENSING RECEPTOR-ACTIVE COMPOUNDS | CASR, CALCR, PTH1R | PTGS1 584/4885PTGS2 958/4885APLNR 300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.