Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 10/20 | 0.81 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.80 |
| ▸ | SNCA | P37840 | 2/20 | 0.70 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.66 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | CA3 | P07451 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.62 |
| ▸ | CA4 | P22748 | 1/20 | 0.62 |
| ▸ | CA6 | P23280 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3208260 | 0.91 | PTGES (0.83) | PTGESMTNR1ASNCATRPA1ALOX5 | |
| SCHEMBL3208266 | 0.91 | PTGES (0.83) | PTGESMTNR1ASNCATRPA1ALOX5 | |
| SCHEMBL18265477 | 0.90 | MTNR1A (1.00) | PTGESMTNR1ASNCATRPA1KDM4E | |
| SCHEMBL16792056 | 0.90 | MTNR1A (1.00) | PTGESMTNR1ASNCATRPA1KDM4E | |
| SCHEMBL16792042 | 0.89 | MTNR1A (0.98) | PTGESMTNR1ASNCATRPA1KDM4E | |
| SCHEMBL18265494 | 0.89 | MTNR1A (0.98) | PTGESMTNR1ASNCATRPA1KDM4E | |
| SCHEMBL9958093 | 0.88 | PTGES (0.79) | PTGESMTNR1ASNCATRPA1ALOX5 | |
| SCHEMBL13168867 | 0.88 | KDM4E (0.75) | PTGESMTNR1ASNCAKDM4EALDH1A1 | |
| SCHEMBL16692678 | 0.87 | PTGES (0.77) | PTGESMTNR1ASNCATRPA1ALOX5 | |
| SCHEMBL18010087 | 0.87 | PTGES (0.77) | PTGESMTNR1ASNCATRPA1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3097904-B1 | DEPIGMENTING AGENTS TO LIGHTEN THE SKIN | AFFICHEM (FR) | 2019-08-14 | — | — | EP | disclosed |
| US-20160375041-A1 | INHIBITION OF ISOPRENOID BIOSYNTHETIC PATHWAYS TO TREAT AUTOIMMUNE DISORDERS | TABACZYNSKI DAVID A (US) | 2016-12-29 | — | — | US | disclosed |
| WO-2016193220-A1 | SKIN PIGMENTATION MODIFIERS TO DARKEN OR LIGHTEN THE SKIN | AFFICHEM (FR) | 2016-12-08 | — | — | WO | disclosed |
| EP-3097904-A1 | DEPIGMENTING AGENTS TO LIGHTEN THE SKIN | Affichem (FR) | 2016-11-30 | — | — | EP | disclosed |
| US-20160303146-A1 | INHIBITION OF ISOPRENOID BIOSYNTHETIC PATHWAYS TO TREAT NEUROINFLAMMATORY DISORDERS | TABACZYNSKI DAVID A (US) | 2016-10-20 | — | — | US | disclosed |
| WO-2015089349-A1 | INHIBITION OF ISOPRENOID BIOSYNTHETIC PATHWAYS TO TREAT NEUROINFLAMMATORY DISORDERS | TABACZYNSKI DAVID A (US) | 2015-06-18 | — | — | WO | disclosed |
| WO-2015084721-A1 | INHIBITION OF ISOPRENOID BIOSYNTHETIC PATHWAYS TO TREAT AUTOIMMUNE DISORDERS | TABACZYNSKI DAVID A (US) | 2015-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160375041-A1 | INHIBITION OF ISOPRENOID BIOSYNTHETIC PATHWAYS TO TREAT AUTOIMMUNE DISORDERS | GGPS1, FDPS, COASY | PTGES 406/4885MTNR1A 3430/4885SNCA 4630/4885 |
| US-20160303146-A1 | INHIBITION OF ISOPRENOID BIOSYNTHETIC PATHWAYS TO TREAT NEUROINFLAMMATORY DISORDERS | GGPS1, FDPS, COASY | PTGES 30/4885MTNR1A 2496/4885SNCA 1652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.