Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4935667 | 0.84 | NR1H2 (0.53) | NR1H2NR1H3FFAR1PTGER4FFAR4 | |
| SCHEMBL4936165 | 0.81 | NR1H2 (0.42) | NR1H2NR1H3FFAR1PTGER4SRD5A2 | |
| SCHEMBL1679381 | 0.81 | NR1H2 (0.34) | ADAMTS4MMP13NR1H2NR1H3FFAR1 | |
| SCHEMBL1679399 | 0.77 | NR1H2 (0.37) | AKR1C3AKR1C2NR1H2NR1H3FFAR1 | |
| SCHEMBL1679283 | 0.76 | NR1H2 (0.51) | ADAMTS4MMP13AKR1C3AKR1C2PTGS2 | |
| SCHEMBL1678766 | 0.75 | AKR1C3 (0.50) | ADAMTS4MMP13AKR1C3AKR1C2PTGS2 | |
| SCHEMBL1679159 | 0.74 | AKR1C3 (0.49) | ADAMTS4MMP13AKR1C3AKR1C2PTGS2 | |
| SCHEMBL1678703 | 0.74 | ADAMTS4 (0.41) | ADAMTS4MMP13AKR1C3AKR1C2PTGS2 | |
| SCHEMBL9628728 | 0.73 | AKR1C3 (0.50) | AKR1C3AKR1C2PTGS2 | |
| SCHEMBL4935619 | 0.73 | RXRA (0.46) | NR1H2NR1H3FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7923573-B2 | Benzene compound having 2 or more substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-04-12 | — | — | US | disclosed |