SCHEMBL1679404

SCHEMBL1679404

O=C(O)C(CCCCCCCCCSSCCCCCCCCCC(C(=O)O)N1C(=O)CCC1=O)N1C(=O)CCC1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
PKM P14618 1/20 0.46
FOLH1 Q04609 2/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC10 Q969S8 1/20 0.33
HDAC11 Q96DB2 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
HDAC9 Q9UKV0 1/20 0.33
HDAC5 Q9UQL6 1/20 0.33
MAPK1 P28482 2/20 0.33
PPM1B O75688 1/20 0.33
KDM4E B2RXH2 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7259685 0.82 ALDH1A1 (0.47) ALDH1A1PKM
SCHEMBL846234 0.82 ALDH1A1 (0.47) ALDH1A1PKMFOLH1CYP1A2CYP2C19
SCHEMBL9410391 0.82 ALDH1A1 (0.47) ALDH1A1PKM
SCHEMBL5698002 0.82 ALDH1A1 (0.47) ALDH1A1PKM
SCHEMBL17821007 0.82 ALDH1A1 (0.47) ALDH1A1PKMFOLH1CYP1A2CYP2C19
SCHEMBL5698006 0.82 ALDH1A1 (0.47) ALDH1A1PKM
SCHEMBL5697931 0.82 ALDH1A1 (0.47) ALDH1A1PKM
SCHEMBL1696971 0.80 ALDH1A1 (0.49) ALDH1A1PKMFOLH1CYP1A2CYP2C19
SCHEMBL28490356 0.80 ALDH1A1 (0.49) ALDH1A1PKMFOLH1CYP1A2CYP2C19
SCHEMBL30773222 0.80 ALDH1A1 (0.49) ALDH1A1PKMFOLH1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110086779-A1 ARRAYS OF PROTEIN CAPTURE AGENTS AND METHODS OF USE THEREOF ZYOMYX, INC. (US) 2011-04-14 US disclosed
US-20090131278-A1 NON-SPECIFIC BINDING RESISTANT PROTEIN ARRAYS AND METHODS FOR MAKING THE SAME ZYOMYX, INC. 2009-05-21 US disclosed
US-20090047695-A1 MICRODEVICES FOR HIGH-THROUGHPUT SCREENING OF BIOMOLECULES ZYOMYX, INC. (US) 2009-02-19 US disclosed
US-20090042744-A1 MICRODEVICES FOR SCREENING BIOMOLECULES ZYOMYX, INC. (US) 2009-02-12 US disclosed
EP-1097379-B1 MICRODEVICES FOR SCREENING BIOMOLECULES ZYOMYX INC (US) 2008-12-31 EP disclosed
EP-1097377-B1 ARRAYS OF PROTEIN-CAPTURE AGENTS AND METHODS OF USE THEREOF ZYOMYX INC (US) 2008-06-04 EP disclosed
US-7247469-B2 Non-specific binding resistant protein arrays and methods for making the same ZYOMYX, INC. (US) 2007-07-24 US disclosed
US-20060228701-A1 Arrays of protein-capture agents and methods of use thereof WAGNER PETER 2006-10-12 US disclosed
US-20060035387-A1 Non-specific binding resistant protein arrays and methods for making the same ZYOMYX, INC. 2006-02-16 US disclosed
US-20050214855-A1 Non-specific binding resistant protein arrays and methods for making the same ZYOMYX, INC. 2005-09-29 US disclosed
US-20020119579-A1 Arrays devices and methods of use thereof ZYOMYX, INC. 2002-08-29 US disclosed
US-20020115225-A1 Microdevices for high-throughput screening of biomolecules ZYOMYX, INCORPORATED 2002-08-22 US disclosed
US-20020110932-A1 Microdevices for screening biomolecules ZYOMYX, INCORPORATED 2002-08-15 US disclosed
US-20020110933-A1 Arrays of proteins and methods of use thereof BILL & MELINDA GATES FOUNDATION 2002-08-15 US disclosed
US-20020106702-A1 Protein arrays for high-throughput screening BILL & MELINDA GATES FOUNDATION 2002-08-08 US disclosed
US-6406921-B1 SUBSTRATE WITH ARRAY OF PROTEIN IMMOBILIZATION REGIONS, HYDROPHILIC BORDER REGIONS AND APPLYING PROTEINS ZYOMYX, INCORPORATED 2002-06-18 US disclosed
US-6365418-B1 Arrays of protein-capture agents and methods of use thereof ZYOMYX, INCORPORATED 2002-04-02 US disclosed
US-6329209-B1 APPARATUS FOR ASSESSING PATTERNS OF PROTEIN EXPRESSION AND MODIFICATION IN CELLS; HAS SPACED-APART IMMOBILIZATION AREAS AND SURROUNDING BORDER AREAS WHICH RESIST NON-SPECIFIC PROTEIN BINDING ZYOMYX, INCORPORATED 2001-12-11 US disclosed
EP-1097380-A1 ARRAYS OF PROTEINS AND METHODS OF USE THEREOF Zyomyx, Inc. (US) 2001-05-09 EP disclosed
WO-2000004382-A1 ARRAYS OF PROTEINS AND METHODS OF USE THEREOF ZYOMYX, INC. (US) 2000-01-27 WO disclosed