Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 20/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30866880 | 0.83 | OPRK1 (0.47) | OPRK1 | |
| SCHEMBL21494392 | 0.83 | OPRK1 (0.47) | OPRK1 | |
| SCHEMBL16795172 | 0.81 | ALK (0.38) | OPRK1 | |
| SCHEMBL26130393 | 0.78 | ALDH1A1 (0.47) | OPRK1 | |
| SCHEMBL29493167 | 0.78 | ALDH1A1 (0.47) | OPRK1 | |
| SCHEMBL390675 | 0.76 | OPRK1 (0.44) | OPRK1 | |
| SCHEMBL390676 | 0.76 | OPRK1 (0.44) | OPRK1 | |
| SCHEMBL26590381 | 0.76 | OPRK1 (0.47) | OPRK1 | |
| SCHEMBL31217395 | 0.75 | PTPN11 (0.45) | OPRK1 | |
| SCHEMBL29969803 | 0.75 | JAK2 (0.44) | OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015086693-A1 | PYRAZOLOPYRIMIDIN-2-YL DERIVATIVES AS JAK INHIBITORS | ALMIRALL, S.A. (ES) | 2015-06-18 | — | — | WO | disclosed |