Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 15/20 | 0.47 |
| ▸ | JAK2 | O60674 | 3/20 | 0.38 |
| ▸ | JAK1 | P23458 | 2/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21494392 | 1.00 | OPRK1 (0.47) | OPRK1JAK2JAK1JAK3PTPN11 | |
| SCHEMBL29969803 | 0.92 | JAK2 (0.44) | OPRK1JAK2JAK1JAK3 | |
| SCHEMBL21513242 | 0.92 | JAK2 (0.44) | OPRK1JAK2JAK1JAK3 | |
| SCHEMBL21513231 | 0.85 | HRH3 (0.42) | OPRK1JAK2JAK1JAK3 | |
| SCHEMBL21513238 | 0.84 | OPRK1 (0.48) | OPRK1 | |
| SCHEMBL29969591 | 0.84 | OPRK1 (0.48) | OPRK1 | |
| SCHEMBL16795122 | 0.83 | OPRK1 (0.50) | OPRK1 | |
| SCHEMBL21513247 | 0.82 | OPRK1 (0.40) | OPRK1 | |
| SCHEMBL29968822 | 0.82 | OPRK1 (0.40) | OPRK1 | |
| SCHEMBL29493167 | 0.78 | ALDH1A1 (0.47) | OPRK1JAK2JAK1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469720-B | Dual ATM and DNA-PK inhibitors for use in anti-tumor therapy | 艾科思莱德制药公司 | 2024-03-29 | — | — | CN | disclosed |