Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844407 | 0.77 | AXL (0.45) | MAPTKDM5ALMNA | |
| SCHEMBL16795275 | 0.70 | KDM4E (0.42) | DRD2DRD4 | |
| SCHEMBL20139993 | 0.67 | DRD2 (0.54) | HTR1ADRD2DRD4KDM5ALMNA | |
| SCHEMBL16795440 | 0.67 | KDM4E (0.41) | MAPTDRD2DRD4 | |
| SCHEMBL17672417 | 0.66 | KDM5A (0.47) | KDM5A | |
| SCHEMBL21832084 | 0.65 | ITGAV (0.45) | — | |
| SCHEMBL27544940 | 0.65 | SMN1; SMN2 (0.44) | MAPTDRD2THRBLMNA | |
| SCHEMBL15942443 | 0.65 | KDM5A (0.47) | CHRM4MAPTDRD2DRD4KDM5A | |
| Hydrochloric Acid SCHEMBL16795310 | 0.65 | HRH4 (0.44) | CHRM4TLR9TLR8TLR7 | |
| SCHEMBL3555476 | 0.65 | CHRM5 (0.54) | MAPTTHRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015086693-A1 | PYRAZOLOPYRIMIDIN-2-YL DERIVATIVES AS JAK INHIBITORS | ALMIRALL, S.A. (ES) | 2015-06-18 | — | — | WO | disclosed |