Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.54 |
| ▸ | DRD4 | P21917 | 10/20 | 0.54 |
| ▸ | HTR1A | P08908 | 9/20 | 0.54 |
| ▸ | KDM5A | P29375 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | HHAT | Q5VTY9 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | UBE2M | P61081 | 1/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139964 | 0.91 | KDM5A (0.58) | DRD2DRD4HTR1AKDM5AKCNH2 | |
| SCHEMBL1740301 | 0.84 | KDM5A (0.48) | DRD2DRD4HTR1AKDM5AKCNH2 | |
| SCHEMBL29556164 | 0.83 | CNR2 (0.41) | DRD2DRD4HTR1AKDM5AKCNH2 | |
| SCHEMBL15140526 | 0.83 | CNR2 (0.41) | DRD2DRD4HTR1AKDM5AKCNH2 | |
| SCHEMBL3737375 | 0.82 | DRD4 (0.39) | DRD2DRD4HTR1AKDM5AKCNH2 | |
| SCHEMBL29924785 | 0.82 | UBE2M (0.41) | DRD2DRD4HTR1AKDM5ACNR2 | |
| SCHEMBL20266326 | 0.82 | UBE2M (0.41) | DRD2DRD4HTR1AKDM5ACNR2 | |
| SCHEMBL29668662 | 0.82 | HTR1A (0.50) | DRD2DRD4HTR1AKDM5AKCNH2 | |
| SCHEMBL9943901 | 0.82 | CNR2 (0.49) | DRD2DRD4HTR1AKDM5ACNR2 | |
| SCHEMBL21597925 | 0.81 | HTR1A (0.53) | DRD2DRD4HTR1AKCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |