Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | PREP | P48147 | 4/20 | 0.36 |
| ▸ | PPARA | Q07869 | 8/20 | 0.33 |
| ▸ | PPARG | P37231 | 7/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679486 | 0.80 | CYP2C19 (0.46) | CYP2C19PPARAPPARGMMP9PDCD1 | |
| SCHEMBL7236135 | 0.74 | PREP (0.40) | CYP2C19PREPPPARAPPARGCD274 | |
| SCHEMBL4945239 | 0.74 | PREP (0.44) | PREPMMP2MMP9MMP12PDCD1 | |
| SCHEMBL29142835 | 0.67 | PREP (0.42) | PREP | |
| SCHEMBL1679693 | 0.67 | CYP2C19 (0.43) | CYP2C19PPARAPPARGMMP9CYP2C9 | |
| SCHEMBL7554485 | 0.66 | PREP (0.39) | CYP2C19PREPPPARAPPARGCYP2C9 | |
| SCHEMBL29962195 | 0.65 | CYP2C19 (0.62) | CYP2C19 | |
| SCHEMBL22394805 | 0.65 | PPARG (0.45) | PPARAPPARGPPARD | |
| SCHEMBL23501346 | 0.65 | KMT2A (0.40) | PREPMMP2MMP9 | |
| SCHEMBL1679080 | 0.64 | MMP2 (0.55) | CYP2C19PPARAPPARGMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7923573-B2 | Benzene compound having 2 or more substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-04-12 | — | — | US | disclosed |