Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | BACE1 | P56817 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.38 |
| ▸ | QDPR | P09417 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16795222 | 0.99 | PABPC1 (0.50) | PABPC1SLC2A1BCHEACHEBACE1 | |
| SCHEMBL25570743 | 0.82 | BCHE (0.56) | PABPC1BCHEACHEBACE1SLC6A4 | |
| SCHEMBL20778600 | 0.79 | BCHE (0.42) | BCHEACHEBACE1SLC6A4SLC6A2 | |
| SCHEMBL16463383 | 0.77 | NPBWR1 (0.49) | PABPC1SLC2A1 | |
| SCHEMBL16795340 | 0.77 | BCHE (0.46) | PABPC1SLC2A1BCHEACHEBACE1 | |
| SCHEMBL16946738 | 0.75 | BCHE (0.46) | PABPC1SLC2A1BCHEACHEBACE1 | |
| SCHEMBL20778735 | 0.75 | CHRM2 (0.39) | BCHEACHEBACE1SLC6A4SLC6A2 | |
| SCHEMBL3355681 | 0.74 | BCHE (0.54) | BCHEACHEBACE1SLC6A4SLC6A2 | |
| SCHEMBL950739 | 0.72 | SLC6A2 (0.49) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL5968212 | 0.72 | SLC6A2 (0.49) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015086693-A1 | PYRAZOLOPYRIMIDIN-2-YL DERIVATIVES AS JAK INHIBITORS | ALMIRALL, S.A. (ES) | 2015-06-18 | — | — | WO | disclosed |