Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.46 |
| ▸ | ACHE | P22303 | 7/20 | 0.46 |
| ▸ | BACE1 | P56817 | 7/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20766340 | 0.86 | BCHE (0.62) | BCHEACHEBACE1SIGMAR1DRD4 | |
| SCHEMBL16269109 | 0.82 | P2RX7 (0.50) | BCHEACHEBACE1 | |
| SCHEMBL3712791 | 0.80 | ACHE (0.60) | BCHEACHEBACE1SIGMAR1DRD4 | |
| SCHEMBL16946738 | 0.78 | BCHE (0.46) | BCHEACHEBACE1PABPC1MAPK14 | |
| SCHEMBL4486493 | 0.77 | P2RX7 (0.48) | BCHEACHEBACE1OPRL1 | |
| SCHEMBL4484252 | 0.77 | TEAD1 (0.45) | BCHEACHEBACE1SIGMAR1OPRL1 | |
| SCHEMBL16795376 | 0.77 | PABPC1 (0.51) | BCHEACHEBACE1PABPC1MAPK14 | |
| SCHEMBL4482088 | 0.77 | OPRL1 (0.53) | BCHEACHEBACE1OPRL1 | |
| Hydrochloric Acid SCHEMBL16795222 | 0.76 | PABPC1 (0.50) | BCHEACHEBACE1PABPC1MAPK14 | |
| SCHEMBL20765886 | 0.75 | BCHE (0.55) | BCHEACHEBACE1SIGMAR1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015086693-A1 | PYRAZOLOPYRIMIDIN-2-YL DERIVATIVES AS JAK INHIBITORS | ALMIRALL, S.A. (ES) | 2015-06-18 | — | — | WO | disclosed |