Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | GPR183 | P32249 | 2/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | MPL | P40238 | 1/20 | 0.39 |
| ▸ | YAP1 | P46937 | 1/20 | 0.39 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.39 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30067540 | 0.83 | HRH4 (0.45) | P2RY14HRH4GPR183ALOX15METAP2 | |
| SCHEMBL27904158 | 0.83 | FLT3 (0.53) | P2RY14HRH4GPR183METAP2MPL | |
| SCHEMBL3643672 | 0.81 | HPGD (0.54) | P2RY14HRH4METAP2IDO1MPL | |
| SCHEMBL29619366 | 0.80 | P2RY14 (0.50) | P2RY14HRH4GPR183PLGPLAU | |
| SCHEMBL16795745 | 0.78 | ALOX15 (0.61) | HRH4GPR183PLGPLAUALOX15 | |
| SCHEMBL926647 | 0.77 | CFTR (0.49) | P2RY14HRH4ALOX15 | |
| SCHEMBL34471210 | 0.77 | CFTR (0.49) | P2RY14HRH4ALOX15 | |
| SCHEMBL29619390 | 0.76 | ALOX15 (0.65) | ALOX15ESR1 | |
| SCHEMBL6173063 | 0.76 | MEN1 (0.50) | P2RY14GPR183ALOX15ESR1 | |
| SCHEMBL2139103 | 0.76 | ALOX15 (0.65) | ALOX15ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015087094-A1 | NEW ARYLALKENYLPROPARGYLAMINE DERIVATIVES EXHIBITING NEUROPROTECTIVE ACTION FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | SEMMELWEIS EGYETEM (HU) | 2015-06-18 | — | — | WO | disclosed |