Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 16/20 | 0.53 |
| ▸ | LPL | P06858 | 1/20 | 0.50 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4659527 | 0.95 | MAOB (0.57) | MAOBLPLLIPGMRGPRX4MAOA | |
| SCHEMBL16795680 | 0.91 | LIPG (0.51) | MAOBLPLLIPGMRGPRX4NR4A2 | |
| SCHEMBL16795672 | 0.88 | LPL (0.51) | MAOBLPLLIPGNR4A2DGAT1 | |
| SCHEMBL16795621 | 0.87 | DGAT1 (0.57) | MAOBLPLLIPGDGAT1 | |
| SCHEMBL4659420 | 0.86 | MAOB (0.56) | MAOBLPLLIPGMAOANR4A2 | |
| SCHEMBL3619300 | 0.84 | DGAT1 (0.57) | MAOBLPLLIPGMAOANR4A2 | |
| SCHEMBL16795630 | 0.83 | MAOB (0.55) | MAOBLPLLIPGMRGPRX4DGAT1 | |
| SCHEMBL21234489 | 0.82 | LPL (0.52) | MAOBLPLLIPGDGAT1 | |
| SCHEMBL20904633 | 0.81 | LIPG (0.57) | LPLLIPG | |
| SCHEMBL24668154 | 0.81 | LPL (0.45) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015087094-A1 | NEW ARYLALKENYLPROPARGYLAMINE DERIVATIVES EXHIBITING NEUROPROTECTIVE ACTION FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | SEMMELWEIS EGYETEM (HU) | 2015-06-18 | — | — | WO | disclosed |