Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL678010 | 0.87 | KDM4E (0.51) | KDM4ESMN1; SMN2CYP19A1CYP2A6RAB9A | |
| SCHEMBL12279056 | 0.81 | HPGDS (0.58) | KDM4ESMN1; SMN2CYP19A1CYP2A6RAB9A | |
| SCHEMBL1424931 | 0.80 | KDM4E (0.75) | KDM4ESMN1; SMN2CYP19A1CYP2A6RAB9A | |
| SCHEMBL1679855 | 0.78 | CYP3A4 (0.49) | KDM4ECYP19A1CYP2A6RAB9ANPC1 | |
| SCHEMBL10181969 | 0.77 | CYP2A6 (0.67) | KDM4ESMN1; SMN2CYP19A1CYP2A6RAB9A | |
| SCHEMBL14654152 | 0.76 | CYP19A1 (0.45) | KDM4ESMN1; SMN2CYP19A1CYP2A6RAB9A | |
| SCHEMBL9973695 | 0.76 | CYP2A6 (0.53) | KDM4ESMN1; SMN2CYP19A1CYP2A6RAB9A | |
| SCHEMBL12278703 | 0.74 | KDM4E (0.66) | KDM4ESMN1; SMN2CYP19A1CYP2A6RAB9A | |
| SCHEMBL12278657 | 0.73 | KDM4E (0.45) | KDM4ESMN1; SMN2CYP19A1CYP2A6RAB9A | |
| SCHEMBL1107870 | 0.73 | CYP2A6 (0.54) | KDM4ESMN1; SMN2CYP19A1CYP2A6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2586311-B1 | Heterocyclic compounds as pest controllers | BAYER CROPSCIENCE AG (DE) | 2016-12-14 | — | — | EP | disclosed |
| EP-2586311-B1 | Heterocyclic compounds as pest controllers | BAYER CROPSCIENCE AG (DE) | 2016-12-14 | — | — | EP | disclosed |
| US-9451775-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-09-27 | — | — | US | disclosed |
| US-9451775-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-09-27 | — | — | US | disclosed |
| US-9451775-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-09-27 | — | — | US | disclosed |
| EP-2583557-B1 | Heterocyclic compounds as pest controllers | BAYER CROPSCIENCE AG (DE) | 2016-01-13 | — | — | EP | disclosed |
| EP-2583557-B1 | Heterocyclic compounds as pest controllers | BAYER CROPSCIENCE AG (DE) | 2016-01-13 | — | — | EP | disclosed |
| US-20140336186-A1 | Heterocyclic Compounds as Pesticides | BAYER CORPSCIENCE AG (DE) | 2014-11-13 | — | — | US | disclosed |
| US-20140336186-A1 | Heterocyclic Compounds as Pesticides | BAYER CORPSCIENCE AG (DE) | 2014-11-13 | — | — | US | disclosed |
| US-20140336186-A1 | Heterocyclic Compounds as Pesticides | BAYER CORPSCIENCE AG (DE) | 2014-11-13 | — | — | US | disclosed |
| EP-2583557-A1 | Heterocyclic compounds as pest controllers | Bayer CropScience AG (DE) | 2013-04-24 | — | — | EP | disclosed |
| EP-2583556-A1 | Heterocyclic compounds as pest controllers | Bayer CropScience AG (DE) | 2013-04-24 | — | — | EP | disclosed |
| EP-2583557-A1 | Heterocyclic compounds as pest controllers | Bayer CropScience AG (DE) | 2013-04-24 | — | — | EP | disclosed |
| EP-2583556-A1 | Heterocyclic compounds as pest controllers | Bayer CropScience AG (DE) | 2013-04-24 | — | — | EP | disclosed |
| US-20110212949-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG | 2011-09-01 | — | — | US | disclosed |
| US-20110212949-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG | 2011-09-01 | — | — | US | disclosed |
| US-20110212949-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG | 2011-09-01 | — | — | US | disclosed |
| EP-2309857-A2 | HETEROCYCLIC COMPOUNDS USED AS PESTICIDES | Bayer CropScience AG (DE) | 2011-04-20 | — | — | EP | disclosed |
| WO-2010006713-A2 | HETEROCYCLIC COMPOUNDS USED AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2010-01-21 | — | — | WO | disclosed |
| WO-2010006713-A2 | HETEROCYCLIC COMPOUNDS USED AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2010-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212949-A1 | Heterocyclic Compounds as Pesticides | DDT, ACHE, PTMS | KDM4E 1877/4885SMN1; SMN2 2082/4885CYP19A1 273/4885 |
| US-20140336186-A1 | Heterocyclic Compounds as Pesticides | DDT, ACHE, PTMS | KDM4E 1877/4885SMN1; SMN2 2082/4885CYP19A1 273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.