Sugi Predict

Sugi Predict / Compounds / SCHEMBL167973

SCHEMBL167973

SCHEMBL167973

O=C1NC(c2cccs2)=C2C(=O)NC(c3cccs3)=C12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC6A11 P48066 1/20 0.44
▸ GSK3B P49841 3/20 0.43
▸ PRKCA P17252 1/20 0.43
▸ LTK P29376 1/20 0.42
▸ CDK5 Q00535 1/20 0.42
▸ MST1R Q04912 1/20 0.42
▸ DYRK1A Q13627 1/20 0.42
▸ CLK4 Q9HAZ1 1/20 0.42
▸ MAOA P21397 2/20 0.40
▸ TYMP P19971 1/20 0.40
▸ HPGD P15428 3/20 0.38
▸ KDM4E B2RXH2 2/20 0.38
▸ MEN1 O00255 2/20 0.38
▸ ALDH1A1 P00352 2/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ MAPT P10636 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ CAMK2D Q13557 1/20 0.37
▸ POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14757441 0.89 SLC6A11 (0.41) SLC6A11GSK3BPRKCALTKCDK5
SCHEMBL2397573 0.88 GSK3B (0.47) SLC6A11GSK3BPRKCALTKCDK5
SCHEMBL12946409 0.87 DPP4 (0.49) SLC6A11GSK3BPRKCALTKCDK5
SCHEMBL12219225 0.87 DPP4 (0.49) SLC6A11GSK3BPRKCALTKCDK5
SCHEMBL15337183 0.87 DPP4 (0.49) SLC6A11GSK3BPRKCALTKCDK5
SCHEMBL12424781 0.87 CYP2E1 (0.41) SLC6A11GSK3BPRKCALTKCDK5
SCHEMBL14757411 0.85 ALDH1A1 (0.40) SLC6A11GSK3BPRKCALTKCDK5
SCHEMBL12424797 0.85 GSK3B (0.51) SLC6A11GSK3BPRKCALTKCDK5
SCHEMBL2607138 0.84 GSK3B (0.38) SLC6A11GSK3BPRKCALTKCDK5
SCHEMBL12178007 0.84 ALDH1A1 (0.49) SLC6A11GSK3BPRKCALTKCDK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 414 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114507336-B Fluorine-containing near infrared absorption conjugated polymer and preparation method thereof 常州大学 2023-08-22 — — CN claimed
CN-110845707-B Pyrrolo-pyrrole mono-keto tetracene analogue polymer and preparation method and application thereof 中山大学 2022-09-09 — — CN claimed
CN-114507336-A Fluorine-containing near-infrared absorption conjugated polymer and preparation method thereof 常州大学 2022-05-17 — — CN claimed
CN-113087877-B Near-infrared two-region fluorescence emission water-soluble conjugated polymer nano phototherapy reagent and preparation method and application thereof 南京邮电大学 2022-03-01 — — CN claimed
US-20210229364-A1 STEREOLITHOGRAPHY WITH MICRON SCALE CONTROL OF PROPERTIES THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE 2021-07-29 — — US claimed
CN-113087877-A Near-infrared two-region fluorescence emission water-soluble conjugated polymer nano phototherapy reagent and preparation method and application thereof 南京邮电大学 2021-07-09 — — CN claimed
CN-109134477-B Aza-tetracene analogue of pyrrole mono-ketone, preparation method and application thereof 中山大学 2021-06-15 — — CN claimed
CN-110526920-B Preparation method of pyrrolopyrroledione derivative 三明学院 2020-12-08 — — CN claimed
US-10723823-B2 Resin formulation and uses thereof AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2020-07-28 — — US claimed
CN-110950894-A D-A-D type organic photo-thermal micromolecule material and preparation method thereof 山西大学 2020-04-03 — — CN claimed
US-20130001476-A1 POLYMERS OF 8,9-DIHYDROBENZO[DEF]CARBAZOLE AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-01-03 — — US claimed
EP-2536700-A2 SEMICONDUCTING POLYMERS Merck Patent GmbH (DE) 2012-12-26 — — EP claimed
US-20120305853-A1 SEMICONDUCTING POLYMERS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-12-06 — — US claimed
WO-2012123060-A1 CONJUGATED POLYMERS MERCK PATENT GMBH (DE) 2012-09-20 — — WO claimed
US-20120118368-A1 Method for Increasing the Efficiency of Organic Photovoltaic Cells BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) 2012-05-17 — — US claimed
WO-2012052099-A1 CONJUGATED POLYMERS MERCK PATENT GMBH (DE) 2012-04-26 — — WO claimed
WO-2012028246-A1 CONJUGATED POLYMERS MERCK PATENT GMBH (DE) 2012-03-08 — — WO claimed
WO-2012003919-A2 SEMICONDUCTING POLYMERS MERCK PATENT GMBH (DE) 2012-01-12 — — WO claimed
WO-2011116866-A1 POLYMERS OF 8,9-DIHYDROBENZO[DEF]CARBAZOLE AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2011-09-29 — — WO claimed
WO-2011098113-A2 SEMICONDUCTING POLYMERS MERCK PATENT GMBH (DE) 2011-08-18 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130001476-A1 POLYMERS OF 8,9-DIHYDROBENZO[DEF]CARBAZOLE AND THEIR USE AS ORGANIC SEMICONDUCTORS DDT, PPOX, DDO SLC6A11 1121/4885GSK3B 1463/4885PRKCA 2563/4885
US-20120305853-A1 SEMICONDUCTING POLYMERS PPOX, OCIAD2, OCIAD1 SLC6A11 2502/4885GSK3B 3393/4885PRKCA 4494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.