Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.52 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.52 |
| ▸ | F3 | P13726 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5950490 | 0.83 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTHPGDPARP10 | |
| SCHEMBL5950494 | 0.83 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTHPGDPARP10 | |
| SCHEMBL14273770 | 0.79 | GSK3B (0.47) | ALDH1A1KDM4EMAPTHPGDPARP10 | |
| SCHEMBL2478128 | 0.78 | PARP10 (0.57) | ALDH1A1PARP10CA1CA2PARP1 | |
| SCHEMBL21754346 | 0.78 | ALDH1A1 (0.59) | ALDH1A1KDM4EMAPTHPGDCA1 | |
| SCHEMBL22259767 | 0.78 | CYP1A2 (0.68) | ALDH1A1KDM4EMAPTHPGDCA1 | |
| SCHEMBL14564661 | 0.77 | GSK3B (0.43) | ALDH1A1KDM4EMAPTHPGDPARP10 | |
| SCHEMBL28158898 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPTHPGDCYP3A4 | |
| SCHEMBL12462506 | 0.75 | APP (0.41) | KDM4EMAPTPARP10CA1CA2 | |
| SCHEMBL7820839 | 0.74 | THRB (0.56) | ALDH1A1KDM4EMAPTHPGDCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090774-A1 | CHEMOTHERAPEUTIC COMPOUNDS AND METHODS OF USE | SEAGEN INC. (US) | 2025-05-01 | — | — | WO | disclosed |
| EP-3079680-A2 | COMPOSITIONS AND METHODS FOR TREATING, PREVENTING AND DIAGNOSING CANCER AND OTHER PROLIFERATIVE DISORDERS | Angiogenex, Inc. (US) | 2016-10-19 | — | — | EP | disclosed |
| WO-2015089495-A2 | COMPOSITIONS AND METHODS FOR TREATING, PREVENTING AND DIAGNOSING CANCER AND OTHER PROLIFERATIVE DISORDERS | ANGIOGENEX, INC. (US) | 2015-06-18 | — | — | WO | disclosed |